EFFECT OF GLUCOSE- INSULIN - POTASSIUM (GIK) SOLUTION ONSHORT TERMPROGNOSIS OF UNSTABLE ANGINA

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ANDISHMAND A.; SADR BAFGHI S.M.; MOTEFAKER MOSTAFA; AZIMI M.R.; AZIMI A.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2007 | Volume:15 | Issue:3 Page(s): 14-19

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Title

EFFECT OF GLUCOSE- INSULIN - POTASSIUM (GIK) SOLUTION ONSHORT TERMPROGNOSIS OF UNSTABLE ANGINA

Author(s)

Keywords

GLUCOSEQ3

INSULINQ3

POTASSIUM (GIK)Q3

UNSTABLE ANGINAQ3

Abstract

Introduction: UNSTABLE ANGINA as a clinical condition includes a major group of patients manifested with acute coronary syndrome. Misdiagnosis of this clinical syndrome causes myocardial infarction (MI) and death.Conventional and advanced forms of treatment are used with the aim of rapid stabilization of UNSTABLE ANGINA. Although infusion of GLUCOSE -insulin -potassium (GIK) solution has had good results in acute MI, no major trial has studied its effect in UNSTABLE ANGINA. The main goal of this study was evaluation of the effectiveness of GIK solution on prognosis of hospitalized UNSTABLE ANGINA patients.Methods: This randomized clinical trial included patients with class II and III UNSTABLE ANGINA (two groups of 94 patients, each) with a mean age of 62.47±13.20 years and Female /Male ratio of 1.35 admitted in the CCU's of Yazd from September 2003 to May 2004.Results: There was no significant difference between the study and control groups regarding mean age, sex ratio and UNSTABLE ANGINA class (P=0.15, P=0.77 and P=0.76). The study group had significant reduction in recurrent chest pain and duration of hospitalization (P=0.001 and P=0.02). The most common adverse effect of GIK solution was pain at infusion site.Conclusion: Use of GIK solution causes early stabilization of UNSTABLE ANGINA patients without any significant or life threatening adverse effect.

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APA: Copy

ANDISHMAND, A., SADR BAFGHI, S.M., MOTEFAKER, MOSTAFA, AZIMI, M.R., & AZIMI, A.. (2007). EFFECT OF GLUCOSE- INSULIN - POTASSIUM (GIK) SOLUTION ONSHORT TERMPROGNOSIS OF UNSTABLE ANGINA. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 15(3), 14-19. SID. https://sid.ir/paper/36696/en

Vancouver: Copy

ANDISHMAND A., SADR BAFGHI S.M., MOTEFAKER MOSTAFA, AZIMI M.R., AZIMI A.. EFFECT OF GLUCOSE- INSULIN - POTASSIUM (GIK) SOLUTION ONSHORT TERMPROGNOSIS OF UNSTABLE ANGINA. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;15(3):14-19. Available from: https://sid.ir/paper/36696/en

IEEE: Copy

A. ANDISHMAND, S.M. SADR BAFGHI, MOSTAFA MOTEFAKER, M.R. AZIMI, and A. AZIMI, “EFFECT OF GLUCOSE- INSULIN - POTASSIUM (GIK) SOLUTION ONSHORT TERMPROGNOSIS OF UNSTABLE ANGINA,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 3, pp. 14–19, 2007, [Online]. Available: https://sid.ir/paper/36696/en

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