Effect of tarragon (Artemisia dracunculus L. ) extract on spatial memory in rats exposed to chronic immobilization stress

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHOSRAVI HAJAR; RAHNEMA MEHDI; Asle Rousta Masoumeh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2019 | Volume:26 | Issue:3 Page(s): 189-197

Download Full-Text

Persian Verion

View:

436

Download:

Cites:

Information Journal Paper

Title

Effect of tarragon (Artemisia dracunculus L. ) extract on spatial memory in rats exposed to chronic immobilization stress

Author(s)

KHOSRAVI HAJAR | RAHNEMA MEHDI | Asle Rousta Masoumeh | Issue Writer Certificate

Keywords

Tarragon (Artemisia dracunculus)Q1

MemoryQ2

Immobilization StressQ2

Abstract

Background and Aim: Tarragon (Artemisia dracunculus L. ) has antioxidant, anti-inflammatory and analgesic effects. The objective of this study was to investigate the effect of Tarragon alcoholic extract on spatial learning and Memory deficits, induced by chronic Immobilization Stress in male rats. Materials and Methods: In this experimental study, 60 male Wistar rats were divided into 6 groups (each group of 10 rats): Control(without treatment), under stress, receiving 100 mg / kg Tarragon extract, receiving 500 mg / kg Tarragon extract, stress receiving and 100 mg / kg Tarragon extract simultaneously, and finally Stress receiving group and 500 mg / kg tarragon extract simultaneously. The rats in under stress group, 6 hours every day for 21 consecutive days they encountered with immobilized stress. Groups receiving Tarragon extract, during this period, the doses of 100 mg / kg. bw and 500 mg / kg. bw were extracted by gavage, and two groups receiving the extract and stress simultaneously, in addition to receiving Tarragon extract at the same doses they also faced stress. Spatial learning and Memory of animals were evaluated by using the Morris Water Maze test. Results Immobilized stress impaired learning and Memory in animals. Delay time (seconds) and distance (cm) moved to reach the hidden platform was significantly increased in the stress group compared to the control group (P <0. 01 and P <0. 05, respectively). Also in probe test, total elapsed time (s) and distance (cm) in target quadrant decreased significantly in stress group compare with control group (p<0. 001 and p<0. 05 respectively). Receiving both doses of Tarragon extract improved spatial learning and Memory in under stressed rats. Conclusion: The results of this study indicate that Tarragon extract prevent Memory impairment and may be useful in preventing and treating of neuro-degenerative diseases due to stress.

Cites

No record.

References

Cite

APA: Copy

KHOSRAVI, HAJAR, RAHNEMA, MEHDI, & Asle Rousta, Masoumeh. (2019). Effect of tarragon (Artemisia dracunculus L. ) extract on spatial memory in rats exposed to chronic immobilization stress. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 26(3 ), 189-197. SID. https://sid.ir/paper/367314/en

Vancouver: Copy

KHOSRAVI HAJAR, RAHNEMA MEHDI, Asle Rousta Masoumeh. Effect of tarragon (Artemisia dracunculus L. ) extract on spatial memory in rats exposed to chronic immobilization stress. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;26(3 ):189-197. Available from: https://sid.ir/paper/367314/en

IEEE: Copy

HAJAR KHOSRAVI, MEHDI RAHNEMA, and Masoumeh Asle Rousta, “Effect of tarragon (Artemisia dracunculus L. ) extract on spatial memory in rats exposed to chronic immobilization stress,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 3 , pp. 189–197, 2019, [Online]. Available: https://sid.ir/paper/367314/en

Related Journal Papers