A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Delbari Yaser; Mohassel Yaser; Bahrami Yadollah; Kakaie Elham; MOSTAFAIE ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2020 | Volume:30 | Issue:186 Page(s): 195-217

Download Full-Text

Persian Verion

View:

587

Download:

Cites:

Information Journal Paper

Title

A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications

Author(s)

Keywords

actinobacteriaQ1

endophytesQ2

bioactive compoundsQ1

drug resistanceQ1

nosocomial infectionsQ2

hospital infectionsQ2

Abstract

Over recent years, nosocomial infections, and the morbidity and mortality associated with pathogenic bacteria have dramatically increased due to antibiotic resistance and imposed significant burdens on the global health system. Critical shortage of effective therapeutics against multidrug-resistant bacteria highlights the need for development of novel antibiotics. actinobacteria are well-known sources of natural bioactive compounds, especially antibiotics. Nearly two-thirds of the antibiotics on the market have actinobacterial origins. Endophytic actinobacteria residing within plants contribute to the plant growth and survival by producing plethora of secondary metabolites. Therefore, isolation, cultivation, and identification of new strains, as well as their potential to produce antimicrobial compounds, are of great importance. Lack of published research in this field highlights the importance of this review in Iran. The aim of this review was to present the latest methods for the isolation and identification of endophytic actinobacteria and introducing relevant databases. We also studied the most recent isolated strains, chemical structure of 51 newly identified secondary metabolites, and their potential medical-pharmaceutical applications. This study revealed that endophytic actinobacteria are prolific sources of bioactive secondary metabolites with high levels of structural diversity and potent pharmaceutical and medicinal applications.

Cites

No record.

References

No record.

Cite

APA: Copy

Delbari, Yaser, Mohassel, Yaser, Kakaie, Elham, & MOSTAFAIE, ALI. (2020). A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 30(186 ), 195-217. SID. https://sid.ir/paper/367674/en

Vancouver: Copy

Delbari Yaser, Mohassel Yaser, Kakaie Elham, MOSTAFAIE ALI. A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;30(186 ):195-217. Available from: https://sid.ir/paper/367674/en

IEEE: Copy

Yaser Delbari, Yaser Mohassel, Elham Kakaie, and ALI MOSTAFAIE, “A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 30, no. 186 , pp. 195–217, 2020, [Online]. Available: https://sid.ir/paper/367674/en

Related Journal Papers