Investigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities

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Karimi Sarah; Raoufi Setareh; BAGHER ZOHREH

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Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2020 | Volume:27 | Issue:12 Page(s): 2215-2228

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Information Journal Paper

Title

Investigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities

Author(s)

Karimi Sarah | Raoufi Setareh | BAGHER ZOHREH | Issue Writer Certificate

Keywords

AgingQ2

Stem cellsQ2

Aging mechanismsQ1

Abstract

Introduction: Aging is a natural phenomenon that is caused by changes in the cells of the body. Theoretically, Aging starts from birth and lasts throughout life. These changes affect the function of the cells. Also, in old tissues, the capacity for homeostasis and tissue repair is decline due to destructive changes in specific tissue Stem cells, niche of Stem cells and systemic factors that regulate stem cell activity. Understanding molecular pathways that disrupt stem cell function during Aging is crucial for the development of new treatments for Aging-associated diseases. In this article, the symptoms of stem cell Aging and the key molecular pathways that are commonly used for the Aging of Stem cells were discussed. We will consider experimental evidence for all of the mechanisms and evaluate the way that can slow down or even stop the Aging process. Finally, we will look at the Aging process of three types of Stem cells.

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APA: Copy

Karimi, Sarah, Raoufi, Setareh, & BAGHER, ZOHREH. (2020). Investigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 27(12 ), 2215-2228. SID. https://sid.ir/paper/36779/en

Vancouver: Copy

Karimi Sarah, Raoufi Setareh, BAGHER ZOHREH. Investigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(12 ):2215-2228. Available from: https://sid.ir/paper/36779/en

IEEE: Copy

Sarah Karimi, Setareh Raoufi, and ZOHREH BAGHER, “Investigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 12 , pp. 2215–2228, 2020, [Online]. Available: https://sid.ir/paper/36779/en

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