COMPARISON OF CLOZAPINE AND HALOPERIDOL EFFECTS ON POSITIVE AND NEGATIVE SYMPTOMS OF CHRONIC SCHIZOPHRENIA

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GOUDARZI I.; PARTOVI GH.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2005 | Volume:7 | Issue:2 Page(s): 0-0

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Title

COMPARISON OF CLOZAPINE AND HALOPERIDOL EFFECTS ON POSITIVE AND NEGATIVE SYMPTOMS OF CHRONIC SCHIZOPHRENIA

Author(s)

GOUDARZI I. | PARTOVI GH. | Issue Writer Certificate

Keywords

CLOZAPINEQ3

HALOPERIDOLQ3

PANSSQ3

POSITIVE AND NEGATIVE SYMPTOMSQ3

SCHIZOPHRENIAQ3

Abstract

Background and Aim: There are controversy about the advantages and disadvantages of new psychiatric drugs, particularly about CLOZAPINE in comparison to other drugs. The aim of this study was to compare the effects of CLOZAPINE and HALOPERIDOL on POSITIVE AND NEGATIVE SYMPTOMS of chronic schizophrenic patients hospitalized in Sina Psychiatric Center, Chahrmahal and Bakhtiary province, Iran. Methods: Sixty schizophrenic patients were divided into two equal groups. One group received CLOZAPINE (200 mg/day) and the second group received HALOPERIDOL (15 mg /day) for 6 weeks. Symptoms were measured using POSITIVE AND NEGATIVE SYMPTOMS Scale (PANSS). Results: CLOZAPINE was better than HALOPERIDOL in decreasing POSITIVE AND NEGATIVE SYMPTOMS (P<0.05) and CLOZAPINE was better than HALOPERIDOL in treating positive symptoms in females (P<0.05). There was no evidence of any superior efficacy of CLOZAPINE or HALOPERIDOL in treating negative symptoms in females. Conclusion: CLOZAPINE was better than HALOPERIDOL in decreasing POSITIVE AND NEGATIVE SYMPTOMS and should be considered more for the treatment of chronic SCHIZOPHRENIA.

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References

THE EFFECT OF BROMOCRLPTINE ON THE NEGATIVE SYMPTOMS OF SCHIZOPHRENIA: A DOUBLE BLIND STUDY

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APA: Copy

GOUDARZI, I., & PARTOVI, GH.. (2005). COMPARISON OF CLOZAPINE AND HALOPERIDOL EFFECTS ON POSITIVE AND NEGATIVE SYMPTOMS OF CHRONIC SCHIZOPHRENIA. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 7(2), 0-0. SID. https://sid.ir/paper/367944/en

Vancouver: Copy

GOUDARZI I., PARTOVI GH.. COMPARISON OF CLOZAPINE AND HALOPERIDOL EFFECTS ON POSITIVE AND NEGATIVE SYMPTOMS OF CHRONIC SCHIZOPHRENIA. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;7(2):0-0. Available from: https://sid.ir/paper/367944/en

IEEE: Copy

I. GOUDARZI, and GH. PARTOVI, “COMPARISON OF CLOZAPINE AND HALOPERIDOL EFFECTS ON POSITIVE AND NEGATIVE SYMPTOMS OF CHRONIC SCHIZOPHRENIA,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 7, no. 2, pp. 0–0, 2005, [Online]. Available: https://sid.ir/paper/367944/en

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