The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A- I, and Apolipoprotein A- II among Male Wistar Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HASANVAND B.; KARAMI K.; YAGHOUB M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:27 | Issue:2 Page(s): 30-40

Download Full-Text

Persian Verion

View:

384

Download:

Cites:

Information Journal Paper

Title

The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A- I, and Apolipoprotein A- II among Male Wistar Rats

Author(s)

HASANVAND B. | KARAMI K. | YAGHOUB M. | Issue Writer Certificate

Keywords

Apolipoprotein A-IQ1

Apolipoprotein A-IIQ1

Continuous submaximal trainingQ1

High-intensity interval trainingQ1

Abstract

Introdaction: Lipid metabolism disorders, especially raised levels of cholesterol and triglycerides increases the risk of atherosclerosis. This study aimed to investigate the effect of training type including submaximal continuous and highintensity interval training on hepatic gene expression of Apolipoprotein A‐ I, and Apolipoprotein A‐ II in male Wistar rats. Materials & Methods: This experimental study conducted on 24 male Wistar rats with 8 weeks of age and weight range of 200-250 g. They were randomly assigned into three groups of control (n=8), highintensity interval training (n=8), and Continuous submaximal training (n=8). High-intensity interval training protocol included 30-min interval running 3 days a week for 8 weeks (each interval took 4 min with 85-90% of VO2max and 2-min active recovery with 50-60% of VO2max). In addition, submaximal continuous training group (30-60 min) was subjected to 50-55% intensity activity with maximum oxygen consumption. Finally, gene expressions of Apolipoprotein A‐ I and Apolipoprotein A‐ II were measured in this study. Ethics code: IR. SSRI. REC. 1396, 134. Findings: The findings of this study showed an increase in the gene expressions of Apolipoprotein A‐ I in the high-intensity interval (P=0. 034) and Continuous submaximal training groups (P=0. 047), compared to the control group. Moreover, the results of the Bonferroni post-hoc test showed that there was no difference between high-intensity interval and Continuous submaximal training groups (P=0. 9). In addition, the results of this study showed that there was no significant difference among the three groups in terms of the gene expression of Apolipoprotein A‐ II. Discussion & Conclusions: High-intensity interval and Continuous submaximal training can play important roles in reducing cardiovascular disease risks, such as atherosclerosis. This is done by increasing hepatic gene expression of Apolipoprotein A‐ I and the main factor taking cholesterol from the liver and ultimately the high-density lipoprotein receptor.

Cites

Effect of eight weeks of regular aerobic exercise on apolipoprotein AI gene expression and lipid profile indices in obese women

References

No record.

Cite

APA: Copy

HASANVAND, B., KARAMI, K., & YAGHOUB, M.. (2019). The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A- I, and Apolipoprotein A- II among Male Wistar Rats. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 27(2 ), 30-40. SID. https://sid.ir/paper/370734/en

Vancouver: Copy

HASANVAND B., KARAMI K., YAGHOUB M.. The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A- I, and Apolipoprotein A- II among Male Wistar Rats. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;27(2 ):30-40. Available from: https://sid.ir/paper/370734/en

IEEE: Copy

B. HASANVAND, K. KARAMI, and M. YAGHOUB, “The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A- I, and Apolipoprotein A- II among Male Wistar Rats,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 2 , pp. 30–40, 2019, [Online]. Available: https://sid.ir/paper/370734/en

Related Journal Papers