Hemolytic Activity of the Cone Gastraopoda Venom Duct Conotoxin from the Persian Gulf: Conuscoronatus and Conusfrigidus

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAJABI HALIMEH; ZOLGHARNEIN HOSEIN; ROUNAGH MOHAMMAD TAGHI; SAVARI AHMAD; Ranjbar Mohamad Sharif

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MARINE BIOLOGY Year:2018 | Volume:10 | Issue:37 Page(s): 65-76

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

603

Download:

Cites:

Information Journal Paper

Title

Hemolytic Activity of the Cone Gastraopoda Venom Duct Conotoxin from the Persian Gulf: Conuscoronatus and Conusfrigidus

Author(s)

Keywords

ConotoxinQ1

Cone GastraopodaQ1

HemolyticQ1

ConusQ1

Abstract

Conotoxins, are exocrine toxic peptides from the epithelial cells of the Cone Gastraopodavenom duct which, for hunting and defense are synthesized. Conotoxins, are neurotoxins or cytotoxin. Neurotoxins, are agents of the pain reliever in animal models and cytotoxin usually introduced as factors of the anti-tumor. Hemolytic activity of the Conotoxins extractions of two species Conuscoronatus and Conusfrigidus tested. Sampling was done in Zeiton Park, Qeshm Island. The venom ducts were isolated and then homogenized. The mixture centrifuged at 10000 × g for 5 min. Supernatant was considered as extracted venom. Peptides up and down 10 kDa, were isolated by the filter Falcon MWCO 10000 Millipore. Serial concentrations of crude Conotoxin extracts, essences top and bottom 10 kDa were used to examine the Hemolytic activity in 96-well plates on human and fish red blood cells. Hemolytic activity of crude and essences up and down 10 kDa were different and only on human blood, Hemolytical effects were observed. Crude extracts, in low concentrations, have no Hemolytic activity and at a concentration of 1, 000 micrograms per milliliter, the percentage of Hemolytic on human blood, was the species 62% and 38% on C. coronatus and C. frigidus, respectively. The extracts top 10 kDa has more Hemolytic effects than the extracts less than 10 kDa. The effects of Hemolytic of Conotoxin extracts is different according to blood type and cytotoxin activities of the extracts were in high concentrations, so cause the presence of peptide neurotoxins pain in these species, they can use in drugs since are not led to damage on red blood cells.

Cites

No record.

References

No record.

Cite

APA: Copy

RAJABI, HALIMEH, ZOLGHARNEIN, HOSEIN, ROUNAGH, MOHAMMAD TAGHI, SAVARI, AHMAD, & Ranjbar, Mohamad Sharif. (2018). Hemolytic Activity of the Cone Gastraopoda Venom Duct Conotoxin from the Persian Gulf: Conuscoronatus and Conusfrigidus. JOURNAL OF MARINE BIOLOGY, 10(37 ), 65-76. SID. https://sid.ir/paper/371317/en

Vancouver: Copy

RAJABI HALIMEH, ZOLGHARNEIN HOSEIN, ROUNAGH MOHAMMAD TAGHI, SAVARI AHMAD, Ranjbar Mohamad Sharif. Hemolytic Activity of the Cone Gastraopoda Venom Duct Conotoxin from the Persian Gulf: Conuscoronatus and Conusfrigidus. JOURNAL OF MARINE BIOLOGY[Internet]. 2018;10(37 ):65-76. Available from: https://sid.ir/paper/371317/en

IEEE: Copy

HALIMEH RAJABI, HOSEIN ZOLGHARNEIN, MOHAMMAD TAGHI ROUNAGH, AHMAD SAVARI, and Mohamad Sharif Ranjbar, “Hemolytic Activity of the Cone Gastraopoda Venom Duct Conotoxin from the Persian Gulf: Conuscoronatus and Conusfrigidus,” JOURNAL OF MARINE BIOLOGY, vol. 10, no. 37 , pp. 65–76, 2018, [Online]. Available: https://sid.ir/paper/371317/en

Related Journal Papers