The Role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases (Review Article)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Aghasizadeh Malihe; GHAYOUR MOBARHAN MAJID; KAZEMI TOBA; AVAN AMIR; MIRI MOGHADDAM EBRAHIM

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2020 | Volume:27 | Issue:2 Page(s): 118-127

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,079

Download:

Cites:

Information Journal Paper

Title

The Role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases (Review Article)

Author(s)

Keywords

AtherosclerosisQ2

Cardiovascular DiseaseQ2

High Density LipoproteinQ1

LipoproteinQ3

Abstract

High-density Lipoprotein (HDL) is a set of particles with heterogeneous structures that have different functions due to various compounds including surface charge, size, lipid, and protein compounds. Several prospective epidemiological studies have demonstrated that there is a clear inverse relationship between serum HDL concentration and risk of coronary heart disease, despite this relationship, clinical evidence has only challenged the usefulness of higher levels of HDL-C in predicting the risk of Cardiovascular Diseases (CVD) and have proven that the structure of HDL is altered and loosed function. Therefore, extensive research is needed to identify new agents and biomarkers to improve HDL function and reduce the risk of Cardiovascular Disease. Given that the most important function of HDL is to transfer excess cholesterol from peripheral tissues and macrophage cells through a receptor called ABCA1 and direct it to the liver, plays an important role in protecting the formation of atherosclerotic plaque. This molecule can provide a strong protective effect against oxidative damage caused by free radicals with intermittent inhibition of the production of pro-inflammatory oxidized lipids in the intima layer of arteries. There is an inverse relationship between the ability to efflux cholesterol and the prevalence of CVD. The ability to remove cholesterol from macrophages by HDL, it is a crucial criterion for determining HDL performance, and it has a strong inverse relationship with carotid intima-media thickness and coronary artery stenosis in angiography independent of HDL level.

Cites

No record.

References

Cite

APA: Copy

Aghasizadeh, Malihe, GHAYOUR MOBARHAN, MAJID, KAZEMI, TOBA, AVAN, AMIR, & MIRI MOGHADDAM, EBRAHIM. (2020). The Role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases (Review Article). JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 27(2 ), 118-127. SID. https://sid.ir/paper/373246/en

Vancouver: Copy

Aghasizadeh Malihe, GHAYOUR MOBARHAN MAJID, KAZEMI TOBA, AVAN AMIR, MIRI MOGHADDAM EBRAHIM. The Role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases (Review Article). JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(2 ):118-127. Available from: https://sid.ir/paper/373246/en

IEEE: Copy

Malihe Aghasizadeh, MAJID GHAYOUR MOBARHAN, TOBA KAZEMI, AMIR AVAN, and EBRAHIM MIRI MOGHADDAM, “The Role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases (Review Article),” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 2 , pp. 118–127, 2020, [Online]. Available: https://sid.ir/paper/373246/en

Related Journal Papers