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Information Journal Paper

Title

Effects of 8 weeks of high intensity interval and moderate intensity continuous training on serum ICAM-1, CRP and cardiometabolic risk factors in middle-agedmen

Pages

  83-101

Abstract

 Background and Aim: Intracellular adhesion molecules 1 (ICAM-1) is more precise than other inflammatory indices e. g. C reactive protein (CRP) in predicting the future cardiovascular diseases. However, the roles of different types of exercise training on serum ICAM-1 level and also body inflammatory and metabolic states are not fully elucidated in patient with Metabolic syndrome (Mets). Therefore, this study was conducted to investigate the effects of 8 weeks of high intensity interval and moderate intensity Continuous training on serum ICAM-1, CRP and cardiometabolic risk factors in middle-aged men. Materials and Methods: Thirty-four male patients with Mets were randomly divided into three groups including high intensity Interval training (n=12), moderate-intensity Continuous training (n=12) and Control (n=10) groups. The fasting blood sample and some other variables were measured at baseline and also after (at 9 AM) eight weeks of continuous (at 60-70% of RHR) and interval (at 70-75% of RHR) training protocols (3 running sessions / week). Blood glucose and lipids were measured using Pars Azmoon company enzymatic kits and serum ICAM-1 and CRP levels also detected with Cusabio company ELIZA kits. Data were analyzed using one way ANOVA and paired samples t tests at p<0. 05. Results: Both the continuous and Interval training protocols decreased blood ICAM-1 (p=0. 001, p=0. 02), CRP (p=0. 001, p=0. 02), triglyceride (p=0. 001, p=0. 001), fasting blood sugar (p=0. 001, p=0. 001), waist circumference (p=0. 001, p=0. 04), overall Mets z score (p=0. 001, p=0. 001) and HOMA-IR (p=0. 007, p=0. 03) respectively, while HDL was significantly increased (p=0. 001, p=0. 01). However, with regard to HDL (p=0. 005), waist circumference (p=0. 001) and Mets Z score (p=0. 001), moderate-intensity Continuous training showed significantly more effectiveness than high intensity Interval training. Conclusion: In spite of the equal effectiveness of both training protocols upon serum ICAM-1 and CRP, Continuous training had more pronounced effects on waist circumference, blood HDL and overall severity of Mets which makes this protocol a better candidate to be prescribed for patients with Mets.

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    APA: Copy

    AAZALI ALAMDARI, KARIM. (2019). Effects of 8 weeks of high intensity interval and moderate intensity continuous training on serum ICAM-1, CRP and cardiometabolic risk factors in middle-agedmen. JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT, 6(12 ), 83-101. SID. https://sid.ir/paper/375319/en

    Vancouver: Copy

    AAZALI ALAMDARI KARIM. Effects of 8 weeks of high intensity interval and moderate intensity continuous training on serum ICAM-1, CRP and cardiometabolic risk factors in middle-agedmen. JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT[Internet]. 2019;6(12 ):83-101. Available from: https://sid.ir/paper/375319/en

    IEEE: Copy

    KARIM AAZALI ALAMDARI, “Effects of 8 weeks of high intensity interval and moderate intensity continuous training on serum ICAM-1, CRP and cardiometabolic risk factors in middle-agedmen,” JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT, vol. 6, no. 12 , pp. 83–101, 2019, [Online]. Available: https://sid.ir/paper/375319/en

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