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Information Journal Paper

Title

Evaluation of Tuberculosis Recurrence and Its Determinants in the Southeast of Iran: A Nested Case-Control Study Based on Data from 2012 to 2018

Pages

  20-29

Abstract

 Background and Objectives: In addition to effective treatment, Tuberculosis Recurrence is a very important challenge regarding the treatment of this infection. This study was conducted to evaluate the risk factors associated with Tuberculosis Recurrence. Methods: In this Nested case-control Study, 202 Tuberculosis patients with Recurrence and 202 matched controls in terms of age, sex and place of residence were studied. The cases and controls were selected from a cohort of Tuberculosis patients in Sistan and Baluchestan province between 2011 and 2018. The data were collected using interviews and patients’ records. The independent t-test, chi-square and multiple conditional logistic regression were used to analyze the data. Results: The drug abuse history (OR=6. 1), 3+ smear positive (OR=3. 03), chest X-ray suggestive of Tuberculosis (OR=4. 9), drug resistance (OR=7. 3), low socioeconomic status (OR=3. 9), weight loss (OR=3. 1), chest pain (OR=3. 2), history of digestive disease (OR=22. 1), smoking (OR=6. 1), and imprisonment (OR=3. 7) significantly increased the chance of Recurrence among Tuberculosis patients (p<0. 05). On the other hand, the chance of Recurrence was significantly lower in patients with coughs (OR=0. 29) and a small family size (OR=0. 28). Conclusion: According to the results, tobacco use, drug use, low socio-economic status, life conditions, and disease conditions are the most important determinants of Tuberculosis Recurrence. In general, epidemiologic factors related to Tuberculosis Recurrence are not similar in different regions; therefore, educational programs for patients and their families and prevention methods should be considered based on related factors in different regions.

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    APA: Copy

    Moatamedizadeh, B., Ansardi, H., PAYANDEH, A., TABATABAE, S.M., & Ramazanpouramirdehi, A.. (2020). Evaluation of Tuberculosis Recurrence and Its Determinants in the Southeast of Iran: A Nested Case-Control Study Based on Data from 2012 to 2018. IRANIAN JOURNAL OF EPIDEMIOLOGY, 16(1 ), 20-29. SID. https://sid.ir/paper/376215/en

    Vancouver: Copy

    Moatamedizadeh B., Ansardi H., PAYANDEH A., TABATABAE S.M., Ramazanpouramirdehi A.. Evaluation of Tuberculosis Recurrence and Its Determinants in the Southeast of Iran: A Nested Case-Control Study Based on Data from 2012 to 2018. IRANIAN JOURNAL OF EPIDEMIOLOGY[Internet]. 2020;16(1 ):20-29. Available from: https://sid.ir/paper/376215/en

    IEEE: Copy

    B. Moatamedizadeh, H. Ansardi, A. PAYANDEH, S.M. TABATABAE, and A. Ramazanpouramirdehi, “Evaluation of Tuberculosis Recurrence and Its Determinants in the Southeast of Iran: A Nested Case-Control Study Based on Data from 2012 to 2018,” IRANIAN JOURNAL OF EPIDEMIOLOGY, vol. 16, no. 1 , pp. 20–29, 2020, [Online]. Available: https://sid.ir/paper/376215/en

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