EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, TESTOSTERONE AND CORTISOL IN YOUNG MEN

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GHARAKHANLOU R.; SAREMI ABAS; OMIDFAR K.; SHARGHI S.; GHARAATI MOHAMMAD REZA

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Journal: OLYMPIC Year:2008 | Volume:16 | Issue:3 (SERIAL 43) Page(s): 31-43

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Title

EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, TESTOSTERONE AND CORTISOL IN YOUNG MEN

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Keywords

MYOSTATINQ2

TESTOSTERONEQ2

CORTISOLQ2

SKELETAL MUSCLEQ2

RESISTANCE TRAININGQ2

Abstract

MYOSTATIN, a potent negative regulator of SKELETAL MUSCLE growth, play important role in the regulation of muscle mass. However, the mechanisms by which muscle MYOSTATIN production is regulated have not been fully understood. The purpose of this study was to determine the effect of eight weeks RESISTANCE TRAINING on changes of serum MYOSTATIN, CORTISOL and TESTOSTERONE levels, muscle strength and lean body mass in untrained young men. Sixteen young men (age: 22.5±2.9 yr) were assigned to RESISTANCE TRAINING (n=8) or control (n=8) groups. The training protocol consisted of thrice weekly using three sets of eight to ten repetition at 60-70% of 1RM for whole-body exercise, whereas control group performed no RESISTANCE TRAINING. Blood sampling, muscular strength test and body composition analysis (DEXA), were performed at 0, 4th and 8th weeks. One-way ANOVA with repeated measurement and bivariate correlation showed that RESISTANCE TRAINING caused significant increase in muscular strength, lean body mass and TESTOSTERONE, whereas CORTISOL and MYOSTATIN were decreased (P<0.05), and there were also negative and positive correlations (r=-0.69, P<0.05) between changes of serum MYOSTATIN with TESTOSTERONE and MYOSTATIN with CORTISOL after RESISTANCE TRAINING, respectively. These data demonstrate that serum MYOSTATIN levels are reduced in response to RESISTANCE TRAINING, and RESISTANCE TRAINING-iduced alterations in MYOSTATIN, TESTOSTERONE and CORTISOL levels may have a role in increases muscle strength and mass.

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APA: Copy

GHARAKHANLOU, R., SAREMI, ABAS, OMIDFAR, K., SHARGHI, S., & GHARAATI, MOHAMMAD REZA. (2008). EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, TESTOSTERONE AND CORTISOL IN YOUNG MEN. OLYMPIC, 16(3 (SERIAL 43)), 31-43. SID. https://sid.ir/paper/37707/en

Vancouver: Copy

GHARAKHANLOU R., SAREMI ABAS, OMIDFAR K., SHARGHI S., GHARAATI MOHAMMAD REZA. EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, TESTOSTERONE AND CORTISOL IN YOUNG MEN. OLYMPIC[Internet]. 2008;16(3 (SERIAL 43)):31-43. Available from: https://sid.ir/paper/37707/en

IEEE: Copy

R. GHARAKHANLOU, ABAS SAREMI, K. OMIDFAR, S. SHARGHI, and MOHAMMAD REZA GHARAATI, “EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, TESTOSTERONE AND CORTISOL IN YOUNG MEN,” OLYMPIC, vol. 16, no. 3 (SERIAL 43), pp. 31–43, 2008, [Online]. Available: https://sid.ir/paper/37707/en

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