Comparison of anesthesia by sodium thiopental with propofol in reducing the need for opiate after tibiofibular fracture surgery

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MirHamidi Seyed Mahdi; ASADI ATEFEH; NEMAT SHAHI MAHBOBEH; NEMATSHAHI MOHAMMAD; YOUSEFI MOGHADAM MANIZHEH; SOROOSH DAVOOD; TAJABADI ALI; Abdulalizadeh Adela

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Journal: Journal of Sabzevar University of Medical Sciences Year:2020 | Volume:27 | Issue:2 Page(s): 295-302

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Title

Comparison of anesthesia by sodium thiopental with propofol in reducing the need for opiate after tibiofibular fracture surgery

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ThiopentalQ3

PropofolQ3

OpiateQ2

Abstract

Introduction: Thiopental Sodium is a commonly used drug in anesthesia, but it is not ideal because barbiturate is prohibited in acute and allergic porphyria, and is not recommended in asthmatic and hypovolemic patients. Propofol is the newest drug in anesthesia due to its rapid onset, short duration of action, anti-nausea and a feeling comfort after use, its consumption is increasing. It is also safe in porphyry and asthma. This study compares the use of sodium antiproliferative drug Propofol to reduce the need for Opiate. Materials and Methods: This study was conducted on 173 patients admitted to Sabzevar Hospital. Patients were randomly divided into two study and control groups. Anesthesia induction was performed in the study group with Propofol 2. 2 kg / mg and with Thiopental sodium 5 kg / mg, in both groups, blood pressure and heart beats were measured before and after induction and minutes 1, 5 and 11 after intubation. Within 1-2-3-4 hours after operation with a pain control chart, the intensity of the pain was checked and the data were recorded. Results: In the Propofol group at the 4th hour, 44 individuals feel mild pain, and 9 had moderate, but severe pain was not reported (P=0/44). In the Thiopental group at the fourth hour, 53 patients feel mild pain, 11 had moderate and 5 had severe pain (P=0/44). Conclusion: Propofol increases the threshold of postoperative pain, so it can be a good alternative to Thiopental.

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APA: Copy

MirHamidi, Seyed Mahdi, ASADI, ATEFEH, NEMAT SHAHI, MAHBOBEH, NEMATSHAHI, MOHAMMAD, YOUSEFI MOGHADAM, MANIZHEH, SOROOSH, DAVOOD, TAJABADI, ALI, & Abdulalizadeh, Adela. (2020). Comparison of anesthesia by sodium thiopental with propofol in reducing the need for opiate after tibiofibular fracture surgery. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 27(2 ), 295-302. SID. https://sid.ir/paper/377305/en

Vancouver: Copy

MirHamidi Seyed Mahdi, ASADI ATEFEH, NEMAT SHAHI MAHBOBEH, NEMATSHAHI MOHAMMAD, YOUSEFI MOGHADAM MANIZHEH, SOROOSH DAVOOD, TAJABADI ALI, Abdulalizadeh Adela. Comparison of anesthesia by sodium thiopental with propofol in reducing the need for opiate after tibiofibular fracture surgery. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(2 ):295-302. Available from: https://sid.ir/paper/377305/en

IEEE: Copy

Seyed Mahdi MirHamidi, ATEFEH ASADI, MAHBOBEH NEMAT SHAHI, MOHAMMAD NEMATSHAHI, MANIZHEH YOUSEFI MOGHADAM, DAVOOD SOROOSH, ALI TAJABADI, and Adela Abdulalizadeh, “Comparison of anesthesia by sodium thiopental with propofol in reducing the need for opiate after tibiofibular fracture surgery,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 2 , pp. 295–302, 2020, [Online]. Available: https://sid.ir/paper/377305/en

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