EVALUATION OF THE EFFICACY OF LYCOPENE IN THE MANAGEMENT OF ORAL LICHEN PLANUS: A PILOT RANDOMIZED CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ARBABI KALATI FATEME; FARAHMAND MOHAMMAD MAHDI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2017 | Volume:75 | Issue:9 Page(s): 658-662

Download Full-Text

Persian Verion

View:

946

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF THE EFFICACY OF LYCOPENE IN THE MANAGEMENT OF ORAL LICHEN PLANUS: A PILOT RANDOMIZED CLINICAL TRIAL

Author(s)

ARBABI KALATI FATEME | FARAHMAND MOHAMMAD MAHDI | Issue Writer Certificate

Keywords

LICHEN PLANUSQ3

LYCOPENEQ1

TREATMENTQ3

Abstract

Background: LICHEN PLANUS is an inflammatory mucocutaneous disease which involves 0. 2‒ 4% of the population and has an unknown etiology. There is no definite TREATMENT for the disease and current TREATMENT modalities are palliative in nature. Although the exact cause of LICHEN PLANUS is not clear, some scientists believe that free radicals and oxidative stress might have a role in causing this condition. The current study was conducted to assess the therapeutic effect of LYCOPENE in treating erosive and atrophic oral LICHEN PLANUS. Methods: Thirty patients whose disease was confirmed by a pathologist were included in the clinical trial from January to July 2016 in the Department of Oral Medicine, Faculty of Dentistry, Zahedan University of Medical Sciences. The patients were randomly divided into two groups. The first group was treated with topical corticosteroid and 15 mg of systemic LYCOPENE daily for a month and the second group received only topical corticosteroids. We recommended that the patients use the drugs (topical corticosteroids) four times a day, avoiding taking food for one hour after applying the drugs. Pain severity was recorded by numeric rating scale before and after the TREATMENT and disease score was recorded by Thongprasom scale before and after TREATMENT. Data were analyzed with SPSS 18. Mann-Whitney U test was used to compare the groups. Results: In the case and control groups, pain scores before TREATMENT were 5. 4± 1. 2 and 5. 7± 0. 9, with 3. 01± 1. 8 and 3. 2± 1. 5 after TREATMENT, respectively. There was no significant difference between the two groups (P= 0. 6, P= 0. 4). Disease scores before TREATMENT were 4. 1± 1 and 4± 0. 8, with 1. 7± 1. 2 and 1. 8± 1. 5 after TREATMENT, respectively. There was no significant difference between the groups (P= 0. 7, P= 0. 8). Conclusion: In this study the use of systemic LYCOPENE did not increase the effect of topical corticosteroid; in addition, the results showed that the systemic use of 15 mg of LYCOPENE in addition to topical corticosteroid TREATMENT had no significant effect on patients’ pain and disease scores in comparison to topical corticosteroids.

Cites

Oral Lichen Planus or Oral Lichenoid Reaction? A Literature Review

References

ROLE OF LYCOPENE IN PREVENTING ORAL DISEASES AS A NONSURGICAL AID OF TREATMENT

Cite

APA: Copy

ARBABI KALATI, FATEME, & FARAHMAND, MOHAMMAD MAHDI. (2017). EVALUATION OF THE EFFICACY OF LYCOPENE IN THE MANAGEMENT OF ORAL LICHEN PLANUS: A PILOT RANDOMIZED CLINICAL TRIAL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 75(9 ), 658-662. SID. https://sid.ir/paper/38035/en

Vancouver: Copy

ARBABI KALATI FATEME, FARAHMAND MOHAMMAD MAHDI. EVALUATION OF THE EFFICACY OF LYCOPENE IN THE MANAGEMENT OF ORAL LICHEN PLANUS: A PILOT RANDOMIZED CLINICAL TRIAL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2017;75(9 ):658-662. Available from: https://sid.ir/paper/38035/en

IEEE: Copy

FATEME ARBABI KALATI, and MOHAMMAD MAHDI FARAHMAND, “EVALUATION OF THE EFFICACY OF LYCOPENE IN THE MANAGEMENT OF ORAL LICHEN PLANUS: A PILOT RANDOMIZED CLINICAL TRIAL,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 75, no. 9 , pp. 658–662, 2017, [Online]. Available: https://sid.ir/paper/38035/en

Related Journal Papers