Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial

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KAVIANNEZHAD RASOOL; AMINI SAMAN JAVAD; MOHAMMADI SAEED; Amini Shila; MIRZAEI MARYAM; Karimpour Hasan Ali

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Journal: Scientific Journal of Kurdistan University of Medical Sciences Year:2020 | Volume:25 | Issue:1 (105) Page(s): 93-104

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Title

Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial

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Keywords

Oral HygieneQ2

PneumoniaQ1

Intensive Care UnitQ2

Endotracheal TubeQ3

Abstract

Background and Aim: Ventilator-associated Pneumonia is a common, serious and costly complication in patients of Intensive Care Units. Oral Hygiene is one of the important clinical measures to reduce the amount of pulmonary infection in these patients. Therefore, this study compares the effects of chlorhexidine and orthodontal mouthwashes on prevention of pulmonary infection in patients with endotracheal tracheal intubation under mechanical ventilation in Intensive Care Units. Materials and Methods: This double-blind clinical trial study was performed on 60 patients undergoing mechanical ventilation in two groups of intervention (n = 30) and control (n = 30) in ICU department of Imam Reza hospital in Kermanshah. In the control group, chlorhexidine (0. 2%) mouthwash and in the intervention group, Ortodontol mouthwash was used three times a day. Data on the rate of early and late Pneumonia were compared based on CPIS criteria applying t-test and Chi-square. Results: The incidence of early and delay Pneumonia in the intervention group was lower than that of control, but no significant difference was observed (P >0. 05). The overall frequency of pulmonary infection in the intervention group was significantly lower than the control group (P = 0. 03). The frequency of Pneumonia causes was lower in the intervention group, but this decrease was statistically significant in Staphylococcus aureus (P = 0. 03). Conclusion: According to the results of this study, orthodontol mouthwash can be effective in reducing the incidence of pulmonary infection associated with mechanical ventilation.

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APA: Copy

KAVIANNEZHAD, RASOOL, AMINI SAMAN, JAVAD, MOHAMMADI, SAEED, Amini, Shila, MIRZAEI, MARYAM, & Karimpour, Hasan Ali. (2020). Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 25(1 (105) ), 93-104. SID. https://sid.ir/paper/380379/en

Vancouver: Copy

KAVIANNEZHAD RASOOL, AMINI SAMAN JAVAD, MOHAMMADI SAEED, Amini Shila, MIRZAEI MARYAM, Karimpour Hasan Ali. Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;25(1 (105) ):93-104. Available from: https://sid.ir/paper/380379/en

IEEE: Copy

RASOOL KAVIANNEZHAD, JAVAD AMINI SAMAN, SAEED MOHAMMADI, Shila Amini, MARYAM MIRZAEI, and Hasan Ali Karimpour, “Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 1 (105) , pp. 93–104, 2020, [Online]. Available: https://sid.ir/paper/380379/en

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