Effects of Vitamin D on Human Body and the Measurement Methods: A Systematic Review

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Hashemniya Veys; Hosseinzade Farzane; Tajik Hurie; Varasteh Abdol Reza; Sharifi Nurie; KEYFI FATEMEH

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Journal: GOVARESH JOURNAL Year:2020 | Volume:25 | Issue:3 Page(s): 208-215

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Title

Effects of Vitamin D on Human Body and the Measurement Methods: A Systematic Review

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Keywords

Vitamin DQ2

Gold standard methodsQ2

Pharmaceutical formsQ1

Vitamin D mechanism of actionQ1

Abstract

Background: Vitamin D is a fat-soluble metabolite, which can be mainly obtained from skin exposure to the sunlight. Foodstuffs containing Vitamin D such as oily fish, eggs, and mushrooms are other sources for this vitamin. Vitamin D plays its role in the body via its intracellular receptor. The discovery of Vitamin D receptors on a wide range of body tissues indicates the broad effects of this metabolite on the human body. The aim of this study was to investigate Vitamin D mechanisms and measurement methods. Materials and Methods: In this study, out of 72 primary articles searched in PubMed and Google Scholar databases from 2012 to 2017, 16 articles with the keywords Vitamin D, gold-standard methods, Pharmaceutical forms, and body organs were selected and studied. Results: Studies have shown the effects of Vitamin D on almost all body organs, including skin, bone, liver, intestine, and muscles. Some hormonal functions are also correlated with Vitamin D. Since Vitamin D deficiency may interfere with numerous mechanisms in the body, taking Vitamin D supplements would have significant effects on preventing many diseases. Conclusions: As Vitamin D deficiency is quite common worldwide, it is recommended to measure Vitamin D levels annually and to take Vitamin D supplements under the supervision of a physician. The reference method used for Vitamin D concentration assessment is liquid chromatography-tandem mass spectrometry. Other measurement techniques have also been used in order to quantify this metabolite, such as immunoassays and chemiluminescence assays.

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APA: Copy

Hashemniya, Veys, Hosseinzade, Farzane, Tajik, Hurie, Varasteh, Abdol Reza, Sharifi, Nurie, & KEYFI, FATEMEH. (2020). Effects of Vitamin D on Human Body and the Measurement Methods: A Systematic Review. GOVARESH JOURNAL, 25(3 ), 208-215. SID. https://sid.ir/paper/381459/en

Vancouver: Copy

Hashemniya Veys, Hosseinzade Farzane, Tajik Hurie, Varasteh Abdol Reza, Sharifi Nurie, KEYFI FATEMEH. Effects of Vitamin D on Human Body and the Measurement Methods: A Systematic Review. GOVARESH JOURNAL[Internet]. 2020;25(3 ):208-215. Available from: https://sid.ir/paper/381459/en

IEEE: Copy

Veys Hashemniya, Farzane Hosseinzade, Hurie Tajik, Abdol Reza Varasteh, Nurie Sharifi, and FATEMEH KEYFI, “Effects of Vitamin D on Human Body and the Measurement Methods: A Systematic Review,” GOVARESH JOURNAL, vol. 25, no. 3 , pp. 208–215, 2020, [Online]. Available: https://sid.ir/paper/381459/en

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