EVALUATING CLINICO-PATHOLOGIC CHARACTERISTICS OF GENITAL SARCOMA: A RETROSPECTIVE STUDY IN MASHHAD

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HASANZADEH MOFRAD MALIHE; HOMAEEI FATEMEH; ESMAELE HABIBOLLAH; AYATE SEDEGEH; NAGAVE REABE HOGGAT

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2011 | Volume:68 | Issue:12 Page(s): 743-747

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Title

EVALUATING CLINICO-PATHOLOGIC CHARACTERISTICS OF GENITAL SARCOMA: A RETROSPECTIVE STUDY IN MASHHAD

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Keywords

GENITAL TRACT SARCOMAQ3

CLINICAL PRESENTATIONSQ3

AGEQ3

TUMOR STAGEQ3

Abstract

Background: Female GENITAL TRACT SARCOMAs are rare but most aggressive tumors of mesodermal origin. Little is known about the pathogenesis, risk factors, optimal treatment and outcome of these diseases. Therefore, we aimed to evaluate the clinicopathologic characteristics of patients with genital sarcoma.Methods: This is a retrospective, cross-sectional study. The medical records of 43 female patients with GENITAL TRACT SARCOMA, hospitalized during a 16-year period (from 1991-2007) were retrieved from the medical records office of Ghaem Hospital in Mashad, Iran. The demographic data extracted from the records.Results: The mean AGE of the patients was 46.95 years (ranging from 3-77 years). The chief complaint of the patients was abnormal vaginal bleeding (69.8%). The mean interval between the onset of symptom to the pathological diagnosis of sarcoma was 8.53 months (ranging from 1-36 months). Histologically, the tumors included: leiomyosarcoma (79.1%), endometrial stromal sarcoma (18.6%) and embryonal rhabdomyosarcoma (2.3%). Three patients (7%) were in International Federation of Gynecology and Obstetrics (FIGO) stage I, 20(46.5%) in stage II, 6(14%) in stage III and 14(32.6%) in stage IV. 48.8% of the patients had undergone chemoradiotherapy.Conclusions: In most cases, our patients were referred so late or the disease was recognized very late due to being rare. We should consider this disease for every patient with unusual vaginal bleeding especially in post menopause women who their sonography has reported uterine mass.

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APA: Copy

HASANZADEH MOFRAD, MALIHE, HOMAEEI, FATEMEH, ESMAELE, HABIBOLLAH, AYATE, SEDEGEH, & NAGAVE REABE, HOGGAT. (2011). EVALUATING CLINICO-PATHOLOGIC CHARACTERISTICS OF GENITAL SARCOMA: A RETROSPECTIVE STUDY IN MASHHAD. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 68(12), 743-747. SID. https://sid.ir/paper/38167/en

Vancouver: Copy

HASANZADEH MOFRAD MALIHE, HOMAEEI FATEMEH, ESMAELE HABIBOLLAH, AYATE SEDEGEH, NAGAVE REABE HOGGAT. EVALUATING CLINICO-PATHOLOGIC CHARACTERISTICS OF GENITAL SARCOMA: A RETROSPECTIVE STUDY IN MASHHAD. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2011;68(12):743-747. Available from: https://sid.ir/paper/38167/en

IEEE: Copy

MALIHE HASANZADEH MOFRAD, FATEMEH HOMAEEI, HABIBOLLAH ESMAELE, SEDEGEH AYATE, and HOGGAT NAGAVE REABE, “EVALUATING CLINICO-PATHOLOGIC CHARACTERISTICS OF GENITAL SARCOMA: A RETROSPECTIVE STUDY IN MASHHAD,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 68, no. 12, pp. 743–747, 2011, [Online]. Available: https://sid.ir/paper/38167/en

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