CLINICAL CHARACTERISTICS, ETIOLOGY, AND DIAGNOSTIC EVALUATION OF EXUDATIVE PLEURISY IN BABOL (1996-2002)

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BIZHANI KH.; HEYDARI- B.; EISSAZADEH M.

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2005 | Volume:62 | Issue:10 Page(s): 835-842

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Title

CLINICAL CHARACTERISTICS, ETIOLOGY, AND DIAGNOSTIC EVALUATION OF EXUDATIVE PLEURISY IN BABOL (1996-2002)

Author(s)

BIZHANI KH. | HEYDARI- B. | EISSAZADEH M. | Issue Writer Certificate

Keywords

PLEURISYQ4

EXUDATIVEQ4

TUBERCULOSISQ4

MALIGNANCYQ4

Abstract

Background: EXUDATIVE pleural effusion (EPE) is a common clinical syndrome in internal medicine. Early diagnosis of EPE is important because it is a common presentation of several diseases with different prognosis. The purpose of the present study is to determine the etiology, clinical characteristics of EPE, and to evaluate the diagnostic methods. Materials and Methods: In this cross-sectional study, patients with EPE hospitalized in pulmonary division of Shaheed Beheshti hospital between 1996 to 2002 were studied. Diagnosis of pleural effusion was verified by clinical examination, Chest x-ray and thoracenthesis. EPE was confirmed by light criteria. Definitive diagnosis of TUBERCULOSIS PLEURISY (TbP) was confirmed by the identification of acid fast bacilli (AFB) from the pleural fluid, biopsy sample or histological findings of granulomas with causes necrosis concomitant with compatible clinical and radiographic findings. Malignant pleural effusion (MP) was verified by finding bf tumor cells from the pleural fluid or tissue specimens. Other diseases were diagnosed by appropriate clinical and laboratory findings. Results: 100 consecutive patients (male, 62%) with EPE with mean age of 5717 (12-82) years were studied. Right sided PLEURISY was observed in 44% and both sides in 5% of patients. The most common causes of EPE were malignant diseases and TUBERCULOSIS which accounted for 41% and 33% of cases respectively. 95.3% of MP were due to met static caners and 4.6% were due to malignant mesothelioma. Other causes which accounted for 24% of patients included; parapnemonic effusion (6%), heart failure (3%), coronary bypass surgery comp0lication (2%). Rheumatoid arthritis (2%), lupus erythematos (1%), chronic renal failure (1 %), coexistence of Tb and MALIGNANCY (2%), and unknown etiology (8%). Pleural biopsy was the best diagnostic method for TbP, and pleural fluid cytology was the best diagnostic method of MP. Pleural fluid analysis detected TbP, and MP in 33% and 70% of cases (P<0.001) and pleural biopsy in 70% and 53.5% of cases respectively (P=NS), whereas both tests detected 97% and 91% of cases with Tb and MP. Conclusion: Even in geographic region with a high prevalence rate of TUBERCULOSIS, malignant diseases should be considered as a cause of EPE.

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APA: Copy

BIZHANI, KH., HEYDARI-, B., & EISSAZADEH, M.. (2005). CLINICAL CHARACTERISTICS, ETIOLOGY, AND DIAGNOSTIC EVALUATION OF EXUDATIVE PLEURISY IN BABOL (1996-2002). TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 62(10), 835-842. SID. https://sid.ir/paper/38290/en

Vancouver: Copy

BIZHANI KH., HEYDARI- B., EISSAZADEH M.. CLINICAL CHARACTERISTICS, ETIOLOGY, AND DIAGNOSTIC EVALUATION OF EXUDATIVE PLEURISY IN BABOL (1996-2002). TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2005;62(10):835-842. Available from: https://sid.ir/paper/38290/en

IEEE: Copy

KH. BIZHANI, B. HEYDARI-, and M. EISSAZADEH, “CLINICAL CHARACTERISTICS, ETIOLOGY, AND DIAGNOSTIC EVALUATION OF EXUDATIVE PLEURISY IN BABOL (1996-2002),” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 62, no. 10, pp. 835–842, 2005, [Online]. Available: https://sid.ir/paper/38290/en

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