Circulating Tumor Cells and Their Clinical Significance in Gastric Cancer (Review Article)

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ABDI ESMAT; LATIFI NAVID SAEID; LATIFI NAVID HAMID; Shahabi Farzaneh

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Journal: GOVARESH JOURNAL Year:2019 | Volume:24 | Issue:3 Page(s): 140-146

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Information Journal Paper

Title

Circulating Tumor Cells and Their Clinical Significance in Gastric Cancer (Review Article)

Author(s)

ABDI ESMAT | LATIFI NAVID SAEID | LATIFI NAVID HAMID | Shahabi Farzaneh | Issue Writer Certificate

Keywords

MetastasisQ2

Diagnostic methodsQ1

Gastric cancerQ2

Abstract

Gastric adenocarcinoma is the fourth most common type of cancers and it is the third leading cause of cancer-related death globally. Unfortunately, more than 40% of patients with Gastric cancer (GC) have no response to chemotherapy. The rest resist chemotherapy, which leads to low survival and limited therapeutic options. Circulating tumor cells (CTCs) are originated from the primary tumor and are present in the blood stream. In recent years, CTCs have been discussed as a primary diagnostic marker for Metastasis; therefore, it may act as a diagnostic and prognostic marker for GC. These cells have the ability of self-renewal and can replicate and grow in a manner similar to that of stem cells. To date, the CellSearch system is the only CTC diagnostic technique approved by U. S FDA. The purpose of this study was to provide a comprehensive overview of the methods for detection of CTCs as well as an insight into the clinical significance of CTCs in relation to GC and recent technical advances in identifying and isolating them.

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APA: Copy

ABDI, ESMAT, LATIFI NAVID, SAEID, LATIFI NAVID, HAMID, & Shahabi, Farzaneh. (2019). Circulating Tumor Cells and Their Clinical Significance in Gastric Cancer (Review Article). GOVARESH JOURNAL, 24(3 ), 140-146. SID. https://sid.ir/paper/383176/en

Vancouver: Copy

ABDI ESMAT, LATIFI NAVID SAEID, LATIFI NAVID HAMID, Shahabi Farzaneh. Circulating Tumor Cells and Their Clinical Significance in Gastric Cancer (Review Article). GOVARESH JOURNAL[Internet]. 2019;24(3 ):140-146. Available from: https://sid.ir/paper/383176/en

IEEE: Copy

ESMAT ABDI, SAEID LATIFI NAVID, HAMID LATIFI NAVID, and Farzaneh Shahabi, “Circulating Tumor Cells and Their Clinical Significance in Gastric Cancer (Review Article),” GOVARESH JOURNAL, vol. 24, no. 3 , pp. 140–146, 2019, [Online]. Available: https://sid.ir/paper/383176/en

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