THE EFFECT OF HEROIN ON HISTOLOGIC STRUCTURE OF TESTIS IN MOUSE

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FAZELIPOUR S.; SHAKOUR A.; TOUTIAN Z.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Tehran University Medical Journal Year:2006 | Volume:64 | Issue:3 Page(s): 12-17

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Title

THE EFFECT OF HEROIN ON HISTOLOGIC STRUCTURE OF TESTIS IN MOUSE

Author(s)

FAZELIPOUR S. | SHAKOUR A. | TOUTIAN Z. | Issue Writer Certificate

Keywords

HEROINQ3

MOUSEQ3

HISTOLOGYQ3

TESTISQ3

Abstract

Background: HEROIN is a simple derivative of morphine that is the most used drug in Iran among opioids. Its harmful effects on body organs have been studied. Considering the important effects on the genital system and fertility, studying the effects of HEROIN on testes seems to be necessary.Methods: In this study a total of 30 male mice (Balb/c) were selected and divided into 5 groups of control (Intact, sham I, sham II), experimental I and experimental II. After addiction of the experimental groups to HEROIN via intra peritoneal injection, the histological structures of testes were studied microscopically.Results: Histological study of HEROIN on testes showed that the thickness of the basement membrane of the germinal epithelium and reduction in cell accumulation around some of the somniferous tubules. Irregularity in spermatogonia, spermatocyte and spermatic, increased distance and degeneration in seminiferous tubules were observed. Increasing connective tissue between somniferous tubules, decreased number of leydig cells, with a hypochromatic cytoplasm and reduction in their secretary granules, and congestion of tactical tissue were also observed.Conclusion: The results of this study show that HEROIN used in Iran can result in changes in the structure of testes. Consequently using HEROIN can influence the reproductive system.

Cites

بررسی اثر تزریقی فرمالدیید بر ساختار بافتی بیضه در موش سوری

References

STUDY OF MORPHOLOGICAL CHANGES OF UTERINE HORN OF SURRI MOUSE DEPENDED TO MORPHINE BEFORE PUBERTY AND DURING PUBERTY

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APA: Copy

FAZELIPOUR, S., SHAKOUR, A., & TOUTIAN, Z.. (2006). THE EFFECT OF HEROIN ON HISTOLOGIC STRUCTURE OF TESTIS IN MOUSE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 64(3), 12-17. SID. https://sid.ir/paper/38544/en

Vancouver: Copy

FAZELIPOUR S., SHAKOUR A., TOUTIAN Z.. THE EFFECT OF HEROIN ON HISTOLOGIC STRUCTURE OF TESTIS IN MOUSE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2006;64(3):12-17. Available from: https://sid.ir/paper/38544/en

IEEE: Copy

S. FAZELIPOUR, A. SHAKOUR, and Z. TOUTIAN, “THE EFFECT OF HEROIN ON HISTOLOGIC STRUCTURE OF TESTIS IN MOUSE,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 64, no. 3, pp. 12–17, 2006, [Online]. Available: https://sid.ir/paper/38544/en

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