An Overview of Immunogenetic in Celiac Disease

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Aflatoonian Majid

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Journal Paper

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2020 | Volume:28 | Issue:3 Page(s): 2442-2452

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Information Journal Paper

Title

An Overview of Immunogenetic in Celiac Disease

Author(s)

Aflatoonian Majid | Issue Writer Certificate

Keywords

CeliacQ2

ImmonulogyQ1

GeneticQ2

Abstract

Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are Genetically predisposed. The disease presents with atrophy of the small intestinal mucosa and gastrointestinal and extra-gastrointestinal manifestations. Environmental factors like gluten and Genetic factors such as HLA and non-HLA genes are involved in causing the disease. Mucosal atrophy results from an adaptive and innate immune response to gluten. T-helper, interleukin 15 and tumor necrosisfactor-alpha have a central role in this process. Recognize the risk of Genetic factors and inflammatorymechanisms will help diagnose and treat the disease.

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APA: Copy

Aflatoonian, Majid. (2020). An Overview of Immunogenetic in Celiac Disease. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 28(3 ), 2442-2452. SID. https://sid.ir/paper/386463/en

Vancouver: Copy

Aflatoonian Majid. An Overview of Immunogenetic in Celiac Disease. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;28(3 ):2442-2452. Available from: https://sid.ir/paper/386463/en

IEEE: Copy

Majid Aflatoonian, “An Overview of Immunogenetic in Celiac Disease,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 3 , pp. 2442–2452, 2020, [Online]. Available: https://sid.ir/paper/386463/en

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