Assessment of follicular development of immature mouse ovarian tissue encapsulated in sodium alginate grafted under the kidney capsule

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DEHGHAN M.; SALEHNIA M.; SHAHBAZI SH.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Pathobiology Research Year:2019 | Volume:22 | Issue:3 Page(s): 121-128

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

402

Download:

Cites:

Information Journal Paper

Title

Assessment of follicular development of immature mouse ovarian tissue encapsulated in sodium alginate grafted under the kidney capsule

Author(s)

DEHGHAN M. | SALEHNIA M. | SHAHBAZI SH. | Issue Writer Certificate

Keywords

OvaryQ2

TransplantationQ3

Sodium AlginateQ1

Ovarian FollicleQ1

Cell DeathQ2

Abstract

Aims The present study aimed to evaluate the developmental rate of Ovarian Follicles and the incidence of Cell Death in grafted immature mouse ovarian tissue encapsulated and noncapsulated in Sodium Alginate. Materials and Methods Female (NMRI) mice (n=50) were divided into 3 groups as follows: Group A; the right Ovary was removed and encapsulated in Sodium Alginate then transplanted under kidney capsule, Group B; the right Ovary was removed and without encapsulation transplanted under kidney capsule, in both transplanted groups the left Ovary was intact. Group C; control group, both ovaries were intact. After Transplantation, in the first and fourth estrous cycles at proestrus phase. The morphology of the grafted ovaries, and the percentage of normal follicles were evaluated using hematoxylin and eosin staining. The incidence of apoptosis Cell Death was evaluated by anti-BAX immunohistochemical staining. Findings At first and fourth estrous cycle, almost 99. 5% of follicles had normal morphology and no significant difference was observed between the groups. The follicular development and growth rate in the two grafted groups, was significantly higher than the control group, moreover, these rates were higher in the capsulated group than non-capsulated once (p<0. 05). In spite of the presence of some BAX positive cells in the preantral and antral follicles, there was no remarkable reaction for BAX antibody in the primordial and primary follicles in studied groups. Conclusion Despite the high developmental rat and premature ovarian reserve depletion in grafted groups that can affect the longevity of transplanted tissue, while Sodium Alginate has a positive effect on the follicular development in grafted tissue.

Cites

No record.

References

No record.

Cite

APA: Copy

DEHGHAN, M., SALEHNIA, M., & SHAHBAZI, SH.. (2019). Assessment of follicular development of immature mouse ovarian tissue encapsulated in sodium alginate grafted under the kidney capsule. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 22(3 ), 121-128. SID. https://sid.ir/paper/386486/en

Vancouver: Copy

DEHGHAN M., SALEHNIA M., SHAHBAZI SH.. Assessment of follicular development of immature mouse ovarian tissue encapsulated in sodium alginate grafted under the kidney capsule. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2019;22(3 ):121-128. Available from: https://sid.ir/paper/386486/en

IEEE: Copy

M. DEHGHAN, M. SALEHNIA, and SH. SHAHBAZI, “Assessment of follicular development of immature mouse ovarian tissue encapsulated in sodium alginate grafted under the kidney capsule,” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 22, no. 3 , pp. 121–128, 2019, [Online]. Available: https://sid.ir/paper/386486/en

Related Journal Papers