The effect of eight weeks of High-intensity Interval Training on the gene expression of the myogenic regulatory factors MyF5 and myogenin in the skeletal muscle of rats

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BIGLARI SOHEIL; GAEINI ABBAS ALI

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Journal: Journal of Sport and Exercise Physiology Year:2019 | Volume:11 | Issue:2 Page(s): 109-116

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Title

The effect of eight weeks of High-intensity Interval Training on the gene expression of the myogenic regulatory factors MyF5 and myogenin in the skeletal muscle of rats

Author(s)

BIGLARI SOHEIL | GAEINI ABBAS ALI | Issue Writer Certificate

Keywords

HIITQ1

MyF5Q1

MyogenesisQ1

MyogeninQ1

Real time-PCRQ1

Abstract

Purpose: Myogenesis plays an important role in the skeletal muscle reconstruction and growth. However, the impact of High-intensity Interval Training (HIIT) on the factors of this process is unknown. The purpose of this study was to investigate the effect of 8 weeks HIIT on Myogenesis main factors, i. e. Myogenic Factor 5 )MyF5( and Myogenin in the rat's gastrocnemius muscle. Methods: In this experimental study, sixteen male Wistar rats (at age of 10 weeks, weight= 255 ± 25 gr) were randomly divided into two groups (control (n = 8) and HIIT (n = 8)). HIIT protocol was performed for 40 minutes, three days a week for eight weeks. 48 hours after the last training session, gastrocnemius muscle was extracted and MyF5 and Myogenin gene expression were measured by Real time-PCR. To analyze the data, independent T-test was used. Results: Compared to the control group, MyF5 and Myogenin gene expression significantly increased in the experimental group (P˂ 0. 05). Additionally, gastrocnemius muscle weight in training group was significantly higher than the control group (P˂ 0. 01). Conclusion: It seems that HIIT leads to a significant increase in the expression of MyF5, Myogenin, and gastrocnemius muscle weight in rats.

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APA: Copy

BIGLARI, SOHEIL, & GAEINI, ABBAS ALI. (2019). The effect of eight weeks of High-intensity Interval Training on the gene expression of the myogenic regulatory factors MyF5 and myogenin in the skeletal muscle of rats. PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY, 11(2 ), 109-116. SID. https://sid.ir/paper/386916/en

Vancouver: Copy

BIGLARI SOHEIL, GAEINI ABBAS ALI. The effect of eight weeks of High-intensity Interval Training on the gene expression of the myogenic regulatory factors MyF5 and myogenin in the skeletal muscle of rats. PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY[Internet]. 2019;11(2 ):109-116. Available from: https://sid.ir/paper/386916/en

IEEE: Copy

SOHEIL BIGLARI, and ABBAS ALI GAEINI, “The effect of eight weeks of High-intensity Interval Training on the gene expression of the myogenic regulatory factors MyF5 and myogenin in the skeletal muscle of rats,” PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY, vol. 11, no. 2 , pp. 109–116, 2019, [Online]. Available: https://sid.ir/paper/386916/en

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