Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma

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SAMADANI ALI AKBAR; MANSOUR GHANAEI FARIBORZ; JOUKAR FARAHNAZ; Safizadeh Mahsa; Nourollahi Seyedeh Elham; RASHIDY POUR ALI

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Journal: Koomesh Year:2019 | Volume:21 | Issue:2 (74) Page(s): 215-224

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Title

Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma

Author(s)

Keywords

AdenocarcinomaQ3

Gastric cancerQ2

Hedgehog ProteinsQ1

Gene ExpressionQ2

Abstract

Gastric cancer (GC) is considered as one of the most serious cancers, and in Iran, due to environmental factors in different regions, it has a high frequency. Apart from environmental factors, genetic and epigenetic ones also play a key role in the development of carcinogenesis of GC. In this regard, the study of functioning of the molecular mechanisms involved in the carcinogenesis and also tumorigenesis of this malignancy in different molecular pathways to identify applied biomarkers in early diagnosis is of great importance. Thus, molecular pathways like sonic hedgehog (SHH) may interfere with this type of cancer. In this review, it has attempted to investigate the performance of the fluctuations of these important genes in SHH pathway.

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APA: Copy

SAMADANI, ALI AKBAR, MANSOUR GHANAEI, FARIBORZ, JOUKAR, FARAHNAZ, Safizadeh, Mahsa, Nourollahi, Seyedeh Elham, & RASHIDY POUR, ALI. (2019). Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma. KOOMESH, 21(2 (74) ), 215-224. SID. https://sid.ir/paper/389635/en

Vancouver: Copy

SAMADANI ALI AKBAR, MANSOUR GHANAEI FARIBORZ, JOUKAR FARAHNAZ, Safizadeh Mahsa, Nourollahi Seyedeh Elham, RASHIDY POUR ALI. Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma. KOOMESH[Internet]. 2019;21(2 (74) ):215-224. Available from: https://sid.ir/paper/389635/en

IEEE: Copy

ALI AKBAR SAMADANI, FARIBORZ MANSOUR GHANAEI, FARAHNAZ JOUKAR, Mahsa Safizadeh, Seyedeh Elham Nourollahi, and ALI RASHIDY POUR, “Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma,” KOOMESH, vol. 21, no. 2 (74) , pp. 215–224, 2019, [Online]. Available: https://sid.ir/paper/389635/en

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