RELATION BETWEEN VITAMIN D AND CALCIUM AND POST OPERATION HYPOCALCEMIA IN TOTAL THYROIDECTOMY

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ASEFKABIRI LEILA; ALIBAKHSHI ABBAS; EMAMI RAZAVI SEYED HASSAN; MOHAMMADIFARD MAHTAB; ABDOLLAHI ALIREZA

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2017 | Volume:75 | Issue:3 Page(s): 194-199

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Title

RELATION BETWEEN VITAMIN D AND CALCIUM AND POST OPERATION HYPOCALCEMIA IN TOTAL THYROIDECTOMY

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Keywords

HYPOCALCEMIAQ1

PARATHYROID HORMONEQ2

THYROIDECTOMYQ1

VITAMIN DQ1

Abstract

Background: HYPOCALCEMIA is one of the most prevalent complications following total THYROIDECTOMY. Over recent years, in addition to hormone PARATHYROID HORMONE (PTH), VITAMIN D has been also studied as a factor causing post-total THYROIDECTOMY HYPOCALCEMIA.This survey seeks to study the relationship between the serum level of VITAMIN D before surgery and during post-total THYROIDECTOMY HYPOCALCEMIA.Methods: A group of 57 patients volunteering for total THYROIDECTOMY were studied on Vali-e-Asr Hospital, Tehran, Iran, from March 2013 to March 2015. In all these patients, pre-surgery calcium, VITAMIN D and PARATHYROID HORMONE (PTH) as well as the level of calcium during the post-surgery first two days were measured. Based on objectives of this study, the relationship be-tween pre-surgery VITAMIN D level and postsurgery HYPOCALCEMIA was examined.Results: The average age of patients participating in the survey was 24.1±13.3. They included 19 women (33.3%) and 38 men, total of 40 patients (70.2%). Their average post-surgery calcium level was 9.2±0.77 milligrams per deciliters (mg/dl) and their average VITAMIN D content before the surgery was 42±12.1 nanomole per liter (nmol/l).The average calcium level before the surgery and the first post-surgery day were meaningfully different in terms of statistics (P<0.001). In terms of VITAMIN D, 37 patients (64.9%) had pre-surgery VITAMIN D deficiency and 20 patients (35.1%) had VITAMIN D insufficiency. Of 37 patients with pre-surgery VITAMIN D deficiency, 26 were diagnosed with post-surgery first-day HYPOCALCEMIA and of 20 patients with VITAMIN D insufficiency, 14 suffered post-surgery first-day HYPOCALCEMIA. This difference was not statistically meaningful (P>0.001). Of 37 patients with pre-surgery VITAMIN D deficiency, 31 suffered post-surgery second-day HYPOCALCEMIA and of 20 patients with VITAMIN D insufficiency, 18 suffered second-day HYPOCALCEMIA. This difference was not statistically meaningful either (P>0.001).Conclusion: The current study showed that the serum level of VITAMIN D before total THYROIDECTOMY does not have any role in the occurrence of post-surgery HYPOCALCEMIA which is almost common after this type of surgery.

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APA: Copy

ASEFKABIRI, LEILA, ALIBAKHSHI, ABBAS, EMAMI RAZAVI, SEYED HASSAN, MOHAMMADIFARD, MAHTAB, & ABDOLLAHI, ALIREZA. (2017). RELATION BETWEEN VITAMIN D AND CALCIUM AND POST OPERATION HYPOCALCEMIA IN TOTAL THYROIDECTOMY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 75(3), 194-199. SID. https://sid.ir/paper/39038/en

Vancouver: Copy

ASEFKABIRI LEILA, ALIBAKHSHI ABBAS, EMAMI RAZAVI SEYED HASSAN, MOHAMMADIFARD MAHTAB, ABDOLLAHI ALIREZA. RELATION BETWEEN VITAMIN D AND CALCIUM AND POST OPERATION HYPOCALCEMIA IN TOTAL THYROIDECTOMY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2017;75(3):194-199. Available from: https://sid.ir/paper/39038/en

IEEE: Copy

LEILA ASEFKABIRI, ABBAS ALIBAKHSHI, SEYED HASSAN EMAMI RAZAVI, MAHTAB MOHAMMADIFARD, and ALIREZA ABDOLLAHI, “RELATION BETWEEN VITAMIN D AND CALCIUM AND POST OPERATION HYPOCALCEMIA IN TOTAL THYROIDECTOMY,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 75, no. 3, pp. 194–199, 2017, [Online]. Available: https://sid.ir/paper/39038/en

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