HERPES ENCEPHALITIS DURING PREGNANCY: A CASE REPORT OF MATERNAL DEATH

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POURALI LEILA; KHAZAEE AZADEH; AYATI SEDIGHEH; LAYEGH PARVANEH; DADGAR SALMEH; MIRZA MARJANI FATEMEH; ESMAEELPOUR EHSAN

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2016 | Volume:74 | Issue:1 Page(s): 70-74

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Title

HERPES ENCEPHALITIS DURING PREGNANCY: A CASE REPORT OF MATERNAL DEATH

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Keywords

ECLAMPSIAQ3

ENCEPHALITISQ3

HERPESQ3

PREGNANCYQ3

SEIZURESQ3

Abstract

Background: HERPES ENCEPHALITIS is the most common cause of fatal ENCEPHALITIS in the world which often presents with sudden fever, headache, seizure, focal neurologic symptoms, and consciousness loss. The aim of this study was to report a case of maternal death caused by HERPES ENCEPHALITIS which appropriate antibiotic therapy delayed because of early diagnosis of ECLAMPSIA.Case Presentation: A 16-year-old pregnant woman at 36th weeks of gestation was referred to gynecology emergency department of Ghaem Hospital, Mashhad University of Medical Sciences in 2016. She was admitted due to 4 times of generalized tonicclonic SEIZURES and blood pressure of 140.90 mmHg with diagnosis of ECLAMPSIA. Cesarean section was performed for fetal distress and ECLAMPSIA remote from delivery.6 hours after cesarean section because of higher than 39oC and reduction in consciousness status, she was transferred to intensive care unit (ICU). The first brain magnetic resonance imaging (MRI) was normal. Lumbar puncture (LP) was performed and brain MRI was repeated that increased signal was observed in two sides of basal ganglia.Intravenous acyclovir was administered by possible diagnosis of viral meningoencephalitis.Cerebrospinal fluid (CSF) was positive in terms of HERPES simplex virus type 1 (HSV-1). Unfortunately, the patient died 35 days after hospitalization by diagnosis of HSV-1 ENCEPHALITIS and bilateral infarction with frequent SEIZURES and clinical manifestation of septic shock refractory to treatment.Conclusion: Although the first diagnosis for generalized convulsion during PREGNANCY is ECLAMPSIA, but in case of recurrent and specially atypical SEIZURES and low consciousness level, other diagnosis like meningoencephalitis, brain lesions and cavernous sinus thrombosis (CVT) must be considered and ruled out.

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APA: Copy

POURALI, LEILA, KHAZAEE, AZADEH, AYATI, SEDIGHEH, LAYEGH, PARVANEH, DADGAR, SALMEH, MIRZA MARJANI, FATEMEH, & ESMAEELPOUR, EHSAN. (2016). HERPES ENCEPHALITIS DURING PREGNANCY: A CASE REPORT OF MATERNAL DEATH. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 74(1), 70-74. SID. https://sid.ir/paper/39073/en

Vancouver: Copy

POURALI LEILA, KHAZAEE AZADEH, AYATI SEDIGHEH, LAYEGH PARVANEH, DADGAR SALMEH, MIRZA MARJANI FATEMEH, ESMAEELPOUR EHSAN. HERPES ENCEPHALITIS DURING PREGNANCY: A CASE REPORT OF MATERNAL DEATH. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2016;74(1):70-74. Available from: https://sid.ir/paper/39073/en

IEEE: Copy

LEILA POURALI, AZADEH KHAZAEE, SEDIGHEH AYATI, PARVANEH LAYEGH, SALMEH DADGAR, FATEMEH MIRZA MARJANI, and EHSAN ESMAEELPOUR, “HERPES ENCEPHALITIS DURING PREGNANCY: A CASE REPORT OF MATERNAL DEATH,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 74, no. 1, pp. 70–74, 2016, [Online]. Available: https://sid.ir/paper/39073/en

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