DEVELOPMENT OF A SIMPLE RISK SCORE MODEL TO PREDICT RENAL ARTERY STENOSIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHATAMI SEYYED MOHAMMAD REZA; JALALI ARASH; SADEGHIAN SAEID; ZARE ELMIRA; SHOKOOEI ZADEH FATEMEH; ROSTAMI ELHAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2018 | Volume:76 | Issue:1 Page(s): 33-40

Download Full-Text

Persian Verion

View:

588

Download:

Cites:

Information Journal Paper

Title

DEVELOPMENT OF A SIMPLE RISK SCORE MODEL TO PREDICT RENAL ARTERY STENOSIS

Author(s)

Keywords

ANGIOGRAPHYQ3

PREDICTIVE VALUE OF VARIABLESQ1

RENAL ARTERY STENOSISQ2

RISK ASSESSMENTQ1

Abstract

Background: RENAL ARTERY STENOSIS (RAS) is a known cause of secondary hypertension and renal failure. The most patients with RENAL ARTERY STENOSIS are asymptomatic. So, the exact prevalence of this disease is unknown. The gold standard of diagnosis of RAS is renal ANGIOGRAPHY that is an expensive somewhat hazardous procedure and may revealed nothing. The aim of this study was to develop a simple risk model score to predict significant RAS based on known risk factors. This may enable us to select patients with high probability of having RAS to perform ANGIOGRAPHY.Methods: A total of 4177 patients whom underwent renal ANGIOGRAPHY from April 2001 to March 2016, were randomly assigned to a development and a validation dataset in ratio of 2: 1 respectively. The clinical and laboratory data of patients were analyzed by multivariate regression analysis. The factors of female sex, history of hypertension and glomerular filtration rate were determined as predicting factors and they were assigned a weighted integer, the sum of the integers was a total risk score for each patient. This model was examined at validation set.Results: We retrospectively evaluated all patients undergoing renal artery ANGIOGRAPHY since 15 years ago. We extracted all risk factors of RAS including age, sex, height, weight, and history of diabetes, hypertension and hyperlipidemia. We also looked at coronary or peripheral vascular diseases and presence of heart failure. The age of patients was 63.5±11.2 years and 40% of the patients were female. The significant RAS was defined as 70% or more narrowing of renal artery. The prevalence of RENAL ARTERY STENOSIS was 14.4% and 13.5% in development and validation dataset respectively. The area under curve and confidence interval for final mode in development dataset was 67.9% (65.0-70.8%). The rates of RAS increased with increasing risk score. In 1402 patients in validation dataset the model showed good discrimination power (c statistic=0.76) Conclusion: This model simply assesses the risk of RAS using available information.This model can be used both in clinical and research purposes. The power of model for diagnosis of RAS is estimated to be 72.6% (68.8%-76.4%).

Cites

No record.

References

No record.

Cite

APA: Copy

KHATAMI, SEYYED MOHAMMAD REZA, JALALI, ARASH, SADEGHIAN, SAEID, ZARE, ELMIRA, SHOKOOEI ZADEH, FATEMEH, & ROSTAMI, ELHAM. (2018). DEVELOPMENT OF A SIMPLE RISK SCORE MODEL TO PREDICT RENAL ARTERY STENOSIS. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 76(1 ), 33-40. SID. https://sid.ir/paper/39074/en

Vancouver: Copy

KHATAMI SEYYED MOHAMMAD REZA, JALALI ARASH, SADEGHIAN SAEID, ZARE ELMIRA, SHOKOOEI ZADEH FATEMEH, ROSTAMI ELHAM. DEVELOPMENT OF A SIMPLE RISK SCORE MODEL TO PREDICT RENAL ARTERY STENOSIS. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2018;76(1 ):33-40. Available from: https://sid.ir/paper/39074/en

IEEE: Copy

SEYYED MOHAMMAD REZA KHATAMI, ARASH JALALI, SAEID SADEGHIAN, ELMIRA ZARE, FATEMEH SHOKOOEI ZADEH, and ELHAM ROSTAMI, “DEVELOPMENT OF A SIMPLE RISK SCORE MODEL TO PREDICT RENAL ARTERY STENOSIS,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 76, no. 1 , pp. 33–40, 2018, [Online]. Available: https://sid.ir/paper/39074/en

Related Journal Papers