COMPARISON OF TWO METHODS FOR MECHANICAL BOWEL PREPARATION IN ELECTIVE OPERATIONS OF COLON

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KARIMIAN F.; MOGHADAM YEGANEH J.; AMINIAN A.; PASHA MEYSAMI A.; FAZELY M.S.; KAZEMEINI A.

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2009 | Volume:67 | Issue:4 Page(s): 284-289

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Title

COMPARISON OF TWO METHODS FOR MECHANICAL BOWEL PREPARATION IN ELECTIVE OPERATIONS OF COLON

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Keywords

BOWEL PREPARATIONQ3

POLY ETHYLENE GLYCOLQ3

ELECTIVEQ3

ANASTOMOSISQ3

COLONQ3

COMPLICATIONSQ3

Abstract

Background: Polyethylene glycol (PEG) solution can induce COMPLICATIONS when used as preoperative BOWEL PREPARATION. The aim of this study was to compare two methods for mechanical BOWEL PREPARATION in ELECTIVE operations of COLON.Methods: In a randomized clinical trial, 129 patients elected for ANASTOMOSIS of COLON and referred to the surgical clinic of Imam Khomeini Hospital of Tehran between March2008 and March 2009 were included. They were randomly allocated into two groups ofPEG1 (1liter of PEG or 70gr plus 15 mg bizacodil, n=63) and PEG4 (4 liter of PEG), according to the way of BOWEL PREPARATION; and on the day before surgery, they received oral and IV prophylactic antibiotics and cleared solutions. In the morning of the surgery, they received their medication during 240 minutes. Then, they underwent anastomosic surgery of COLON. The principle variables recorded were nausea, vomiting, flatulence, Na and K in the night before surgery, patients’ and surgeons’ satisfaction from BOWEL PREPARATION and postoperative infection and leakage.Results: The majority of the patients were male (62%). Nausea (28.57% vs.98.48%, p=0.001), flatulence (36.51% vs.95.45%, p=0.001), and vomiting (4.76% vs.75.76%, p=0.001) were significantly lower in PEG1 and the patients’ satisfaction were significantly higher (59.02% vs.1.52%, p=0.001) Peroperative Na was significantly higher inPEG4 group (141.21±3.63 vs.139.94±2.97mg/l, p=0.001) and serum K was significantly lower (3.55±0.25 vs.3.76±0.21, p=0.001). Surgeons’ satisfaction were significantly higher in PEG4 group (good to very good 72.73% vs.43.54%, p=0.001). Postoperative infection of surgical site, ANASTOMOSIS leakage and ICU admission were comparable between study groups.Conclusions: BOWEL PREPARATION with 1 liter of PEG plus 3 bizacodile pills instead of 1 liter of PEG in patients undergoing ELECTIVE ANASTOMOSIS of COLON is not only associated with lesser nausea, vomiting, flatulence, but also increases the patients’ satisfaction and tolerance, lessens electrolyte disturbances and do not influence postoperative infection of surgical site and ANASTOMOSIS leakage.

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APA: Copy

KARIMIAN, F., MOGHADAM YEGANEH, J., AMINIAN, A., PASHA MEYSAMI, A., FAZELY, M.S., & KAZEMEINI, A.. (2009). COMPARISON OF TWO METHODS FOR MECHANICAL BOWEL PREPARATION IN ELECTIVE OPERATIONS OF COLON. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 67(4), 284-289. SID. https://sid.ir/paper/39131/en

Vancouver: Copy

KARIMIAN F., MOGHADAM YEGANEH J., AMINIAN A., PASHA MEYSAMI A., FAZELY M.S., KAZEMEINI A.. COMPARISON OF TWO METHODS FOR MECHANICAL BOWEL PREPARATION IN ELECTIVE OPERATIONS OF COLON. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2009;67(4):284-289. Available from: https://sid.ir/paper/39131/en

IEEE: Copy

F. KARIMIAN, J. MOGHADAM YEGANEH, A. AMINIAN, A. PASHA MEYSAMI, M.S. FAZELY, and A. KAZEMEINI, “COMPARISON OF TWO METHODS FOR MECHANICAL BOWEL PREPARATION IN ELECTIVE OPERATIONS OF COLON,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 67, no. 4, pp. 284–289, 2009, [Online]. Available: https://sid.ir/paper/39131/en

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