COMPARING THE ANALGESIC EFFECTS OF ADDING KETAMINE TO MORPHINE WITH TRAMADOL AFTER MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA

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IMANI FARNAD; ENTEZARY SAEID REZA; FAIZ SEYYED HAMID REZA; ALEBOUYEH MAHMOUD REZA; NIKPOUR KARIM

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Journal: Journal of Anesthesiology and Pain Year:2011 | Volume:2 | Issue:5 Page(s): 0-0

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Title

COMPARING THE ANALGESIC EFFECTS OF ADDING KETAMINE TO MORPHINE WITH TRAMADOL AFTER MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA

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Keywords

PAIN SCOREQ2

MAJOR ABDOMINAL SURGERYQ2

KETAMINEQ3

TRAMADOLQ2

MORPHINEQ3

Abstract

Background: Postoperative pain control is one of the problems for these patients. Opioid agents are the most important analgesics which commonly used for postoperative pain control. There are several trials for reducing the doses of opioids. It seems addition of KETAMINE to the opioids other than postoperative pain relief, reduces the total opioid consumption. The goal of this study was evaluation of postoperative analgesic effects of adding KETAMINE to MORPHINE and TRAMADOL after MAJOR ABDOMINAL SURGERY.Methods: Eighty patients candidate for MAJOR ABDOMINAL SURGERY under similar general anesthesia were enrolled in this study. Postoperative pain was managed by iv patient controlled analgesia (PCA) for aal patients. After the end of surgery, they were randomly allocated into the 1) MORPHINE (M), 2) TRAMADOL (T), 3) KETAMINE and MORPHINE (KM), and 4) KETAMINE and TRAMADOL (KT) groups. Analgesic solution in PCA in M group was MORPHINE (0.2 mg/ml), in T group was TRAMADOL (2 mg/ml), in KM group was KETAMINE (2 mg/ml) and MORPHINE (0.2 mg/ml), and in KT group was KETAMINE (2 mg/ml) and TRAMADOL (2 mg/ml). Visual analogue scale (VAS), total opioid consumption, complications, and satisfaction were measured and recorded for during the first 24 hours after surgery.Results: Demographic data was not differences between groups. PAIN SCORE in early period (1st and 6th hours) was significantly lower in KM group than the others. Furthermore, addition of KETAMINE significantly reduced total MORPHINE and TRAMADOL consumption. No side effects were observed in the all groups.Conclusions: Our finding showed that addition of KETAMINE to MORPHINE could reduce PAIN SCORE and total opioid consumption after MAJOR ABDOMINAL SURGERY.

Cites

EFFECTIVENESS OF ACCEPTANCE AND COMMITMENT THERAPY (ACT) ON ADMISSION OF TREATMENT PLAN IN MARIJUANA, PHENCYCLIDINE AND KETAMINE ABUSERS

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APA: Copy

IMANI, FARNAD, ENTEZARY, SAEID REZA, FAIZ, SEYYED HAMID REZA, ALEBOUYEH, MAHMOUD REZA, & NIKPOUR, KARIM. (2011). COMPARING THE ANALGESIC EFFECTS OF ADDING KETAMINE TO MORPHINE WITH TRAMADOL AFTER MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 2(5), 0-0. SID. https://sid.ir/paper/393269/en

Vancouver: Copy

IMANI FARNAD, ENTEZARY SAEID REZA, FAIZ SEYYED HAMID REZA, ALEBOUYEH MAHMOUD REZA, NIKPOUR KARIM. COMPARING THE ANALGESIC EFFECTS OF ADDING KETAMINE TO MORPHINE WITH TRAMADOL AFTER MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2011;2(5):0-0. Available from: https://sid.ir/paper/393269/en

IEEE: Copy

FARNAD IMANI, SAEID REZA ENTEZARY, SEYYED HAMID REZA FAIZ, MAHMOUD REZA ALEBOUYEH, and KARIM NIKPOUR, “COMPARING THE ANALGESIC EFFECTS OF ADDING KETAMINE TO MORPHINE WITH TRAMADOL AFTER MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 2, no. 5, pp. 0–0, 2011, [Online]. Available: https://sid.ir/paper/393269/en

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