The Effects of Hydro-alcoholic Extracts of Allium sativum L. and Orchismaculata L. on Spermatogenesis Index and Testosterone Level in Cyclophosphamide-treated Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Sadeghzadeh Firouze; Sadeghzadeh Azizieh; CHANGIZI ASHTIYANI SAEED; Alimoradian Abass; Mashayekhei Mehry; ZAREI ALI; JALALI MASHAYEKHI FARIDEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Kerman University of Medical Sciences Year:2020 | Volume:27 | Issue:3 Page(s): 232-243

Download Full-Text

Persian Verion

View:

1,103

Download:

298

Cites:

Information Journal Paper

Title

The Effects of Hydro-alcoholic Extracts of Allium sativum L. and Orchismaculata L. on Spermatogenesis Index and Testosterone Level in Cyclophosphamide-treated Rats

Author(s)

Keywords

InfertilityQ2

GarlicQ2

OrchidQ3

CyclophosphamideQ2

SpermatogenesisQ2

Abstract

Background: One of the most common side effects of Cyclophosphamide (CP) is oligo-spermatozoa, azoospermia and elimination of spermatogenic cycles. This study was done to find the efficacy of simultaneous consumption of Garlic (Allium sativum L. ) and Orchid (Orchismaculata L. ) hydroalcoholic extracts on Spermatogenesis and sex hormones in rats treated with CP. Methods: Forty-two male rats were divided into the six groups: control, sham, CP (5 mg/kg), Garlic (10 mg/kg) + CP, Orchid (40 mg/kg) + CP, Garlic+ Orchid + CP. All of the agents were administered through oral gavage for 28 days. Results: The number of sperms increased in Garlic+ CP and Orchid+ CP groups. The percentage of sperm forward motility increased in groups receiving Garlic, Orchid, and Garlic +Orchid compared with the group that received only CP. Antioxidant total capacity and testosterone level showed significant increases in Garlic+ Orchid, Garlic and Orchid groups respectively compared with the group that received only CP (P<0. 05). Also, the tissue and serum malondialdehyde levels reduced in the group received Garlic +Orchid compared with the group that received only CP. Conclusion: Garlic and Orchid could increase the number and the motility of sperms, index of sertoli cell, antioxidant capacity and serum testosterone level.

Cites

No record.

References

No record.

Cite

APA: Copy

Sadeghzadeh, Firouze, Sadeghzadeh, Azizieh, CHANGIZI ASHTIYANI, SAEED, Alimoradian, Abass, Mashayekhei, Mehry, ZAREI, ALI, & JALALI MASHAYEKHI, FARIDEH. (2020). The Effects of Hydro-alcoholic Extracts of Allium sativum L. and Orchismaculata L. on Spermatogenesis Index and Testosterone Level in Cyclophosphamide-treated Rats. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 27(3), 232-243. SID. https://sid.ir/paper/393746/en

Vancouver: Copy

Sadeghzadeh Firouze, Sadeghzadeh Azizieh, CHANGIZI ASHTIYANI SAEED, Alimoradian Abass, Mashayekhei Mehry, ZAREI ALI, JALALI MASHAYEKHI FARIDEH. The Effects of Hydro-alcoholic Extracts of Allium sativum L. and Orchismaculata L. on Spermatogenesis Index and Testosterone Level in Cyclophosphamide-treated Rats. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(3):232-243. Available from: https://sid.ir/paper/393746/en

IEEE: Copy

Firouze Sadeghzadeh, Azizieh Sadeghzadeh, SAEED CHANGIZI ASHTIYANI, Abass Alimoradian, Mehry Mashayekhei, ALI ZAREI, and FARIDEH JALALI MASHAYEKHI, “The Effects of Hydro-alcoholic Extracts of Allium sativum L. and Orchismaculata L. on Spermatogenesis Index and Testosterone Level in Cyclophosphamide-treated Rats,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 3, pp. 232–243, 2020, [Online]. Available: https://sid.ir/paper/393746/en

Related Journal Papers