SURVEY OF THE PREVALENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN RASHT-IRAN

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KHALILI DAVOUD; JAFROUDI M.; SAJEDI S.A.; SHAMELI RAD M.; ABD ELAHI F.; ALI POUR KANAFI K.; SABAHI E.A.D.; HEZBI A.G.

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Journal: JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES Year:2007 | Volume:16 | Issue:63 Page(s): 51-56

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Title

SURVEY OF THE PREVALENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN RASHT-IRAN

Author(s)

Keywords

EPIDEMIOLOGYQ3

GLUCOSE-6-PHOSPHATEQ3

GLUCOSE PHOSPHATE DEHYDROGENASEQ3

JAUNDICEQ4

NEONATALQ4

Abstract

Introduction: G6PD Deficiency is the most common enzyme deficiency in all over the world. The prevalence of this defect differs in the different parts of the world (from 0.1 to 50 percent). Clinical complications such as Acute Hemolytic Anemia and NEONATAL JAUNDICE are common in areas that materials which have oxidant factor such as Fava bean is used excessively. Objective: Study of the prevalence of this defect in Rasht. Materials and Methods: In this cross-sectional study, 605 male and 585 female neonates were examined by FST (Fluorescent Spot Test) in 17 Shahrivar Hospital. Results: 59 males (9.8%, CI 95%=7.5-12.5%) and 18 females (3.1%, CI 95%= 1.9-4.9%) were detected as G6PD Deficient. Total prevalence was 6.4 percent (CI 95%: 5-8 percent). It is obvious that G6PD Deficiency in males was more than females (p<0.001, RR=3.3). There was no significant relation between G6PD Deficiency and being term or preterm (p>0.1). Conclusion: Because G6PD is sex related, its three times more prevalence in male compared with female in expected. This deficiency is more common in south compared with north of Iran (probably because of malaria) but the excessive use of Fava bean is the main reason for incidence of its complications in this area, then, the wise policy would be screening neonates and instruction parents.

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APA: Copy

KHALILI, DAVOUD, JAFROUDI, M., SAJEDI, S.A., SHAMELI RAD, M., ABD ELAHI, F., ALI POUR KANAFI, K., SABAHI, E.A.D., & HEZBI, A.G.. (2007). SURVEY OF THE PREVALENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN RASHT-IRAN. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 16(63), 51-56. SID. https://sid.ir/paper/39678/en

Vancouver: Copy

KHALILI DAVOUD, JAFROUDI M., SAJEDI S.A., SHAMELI RAD M., ABD ELAHI F., ALI POUR KANAFI K., SABAHI E.A.D., HEZBI A.G.. SURVEY OF THE PREVALENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN RASHT-IRAN. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;16(63):51-56. Available from: https://sid.ir/paper/39678/en

IEEE: Copy

DAVOUD KHALILI, M. JAFROUDI, S.A. SAJEDI, M. SHAMELI RAD, F. ABD ELAHI, K. ALI POUR KANAFI, E.A.D. SABAHI, and A.G. HEZBI, “SURVEY OF THE PREVALENCE OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN RASHT-IRAN,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 63, pp. 51–56, 2007, [Online]. Available: https://sid.ir/paper/39678/en

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