EFFECT OF 8 WEEKS ENDURANCE EXERCISE TRAINING AND HIGH-FAT DIET ON BRAINDERIVED NEUROTROPHIC FACTOR (BDNF) IN MALE ADULT RAT HIPPOCAMPUS

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VOSADI E.; BARZEGAR H.; BORJIAN FARD M.

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Paper Information

Journal: Journal of Arak University Medical Sciences Year:2014 | Volume:16 | Issue:10 (79) Page(s): 0-0

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Title

EFFECT OF 8 WEEKS ENDURANCE EXERCISE TRAINING AND HIGH-FAT DIET ON BRAINDERIVED NEUROTROPHIC FACTOR (BDNF) IN MALE ADULT RAT HIPPOCAMPUS

Author(s)

VOSADI E. | BARZEGAR H. | BORJIAN FARD M. | Issue Writer Certificate

Keywords

RATSQ2

BRAIN-DERIVED NEUROTROPHIC FACTORQ2

HIGH FAT DIETQ2

HIPPOCAMPUSQ2

PHYSICAL ENDURANCEQ2

Abstract

Background: Behaviors and our lifestyles affect the expression of BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF), and experiences associated with emotional health such as exercise and enriched environment lead to increased levels of this important neurotrophin. This study was performed to identify the possible effects of endurance exercise and high-fat diet on levels of BDNF in HIPPOCAMPUS of adult male RATS to clear the role of exercise and nutrition effect on synaptic plasticity.Materials and methods: In this experimental study, twenty eight Wistar RATS were divided into four equal groups including Regular Diet-Sedentary (RD-Sed) as control group, Regular diet-Exercise (RD-Exe), HF-sedentary (HF-Sed), and HF- Exercise (HF- Exe).Animals in exercise groups received 8 weeks endurance training and animals in HF groups were exposed to the HF diet for 8 weeks. Hippocampal BDNF protein was assessed using commercial ELISA kits and the data were analyzed by one-way ANOVA. Statistical differences were considered significant at p<0.05.Results: The results showed that the endurance training had no significant increase in BDNF protein level comparison with the RD-Sd and HF-Sed groups.Conclusion: Based on the results of the present study, it seems that endurance training can increase levels of HIPPOCAMPUS BDNF protein.

Cites

THE EFFECTS OF ENDURANCE TRAININGS ON SERUM BDNF AND INSULIN LEVELS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

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APA: Copy

VOSADI, E., BARZEGAR, H., & BORJIAN FARD, M.. (2014). EFFECT OF 8 WEEKS ENDURANCE EXERCISE TRAINING AND HIGH-FAT DIET ON BRAINDERIVED NEUROTROPHIC FACTOR (BDNF) IN MALE ADULT RAT HIPPOCAMPUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 16(10 (79)), 0-0. SID. https://sid.ir/paper/396872/en

Vancouver: Copy

VOSADI E., BARZEGAR H., BORJIAN FARD M.. EFFECT OF 8 WEEKS ENDURANCE EXERCISE TRAINING AND HIGH-FAT DIET ON BRAINDERIVED NEUROTROPHIC FACTOR (BDNF) IN MALE ADULT RAT HIPPOCAMPUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2014;16(10 (79)):0-0. Available from: https://sid.ir/paper/396872/en

IEEE: Copy

E. VOSADI, H. BARZEGAR, and M. BORJIAN FARD, “EFFECT OF 8 WEEKS ENDURANCE EXERCISE TRAINING AND HIGH-FAT DIET ON BRAINDERIVED NEUROTROPHIC FACTOR (BDNF) IN MALE ADULT RAT HIPPOCAMPUS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 16, no. 10 (79), pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/396872/en

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