Implantation of multiple suprachoroidal electrode arrays in rabbits

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Abdallah Walid; Li Wen; Weiland James; Humayun Mark; ameri hossein

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Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2018 | Volume:30 | Issue:1 Page(s): 68-73

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Title

Implantation of multiple suprachoroidal electrode arrays in rabbits

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Keywords

SuprachoroidalQ3

ElectrodesQ3

ArrayQ3

Retinal prosthesisQ3

Retinal implantQ3

Abstract

Purpose: Epiretinal and subRetinal prosthesis have been shown to be a valid way to provide some vision to patients with advanced outer retinal degeneration and profound vision loss. However, the field of vision for these patients is markedly limited by the area occupied by the electrode Array. In this study, we aimed to evaluate the feasibility of implantation of multiple Suprachoroidal electrode Arrays in a single eye in order to increase the field of vision in patients implanted with Retinal prosthesis. Methods: The right eye of seventeen Dutch rabbits (age range, 5e6 months) was used for the study. Multiple inactive custom-made electrode Arrays were inserted into the Suprachoroidal space (SCS) and animals were followed up for up to 6 months using fundus photography, optical coherence tomography (OCT), and fluorescein angiography (FA). Results: It was possible to surgically implant up to 8 electrode Arrays in a single eye. None of the rabbits showed any major complications. The Electrodes were well tolerated and remained in position in all rabbits. There was no evidence of retinal damage on follow-up exams and FA throughout the study. Conclusion: Multiple Suprachoroidal electrode Array implantation is feasible and may provide a novel approach to increase the field of vision in subjects implanted with Retinal prosthesis.

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IDEAL INCISION FOR CATARACT SURGERY

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APA: Copy

Abdallah, Walid, Li, Wen, Weiland, James, Humayun, Mark, & ameri, hossein. (2018). Implantation of multiple suprachoroidal electrode arrays in rabbits. JOURNAL OF CURRENT OPHTHALMOLOGY, 30(1), 68-73. SID. https://sid.ir/paper/399566/en

Vancouver: Copy

Abdallah Walid, Li Wen, Weiland James, Humayun Mark, ameri hossein. Implantation of multiple suprachoroidal electrode arrays in rabbits. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2018;30(1):68-73. Available from: https://sid.ir/paper/399566/en

IEEE: Copy

Walid Abdallah, Wen Li, James Weiland, Mark Humayun, and hossein ameri, “Implantation of multiple suprachoroidal electrode arrays in rabbits,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 30, no. 1, pp. 68–73, 2018, [Online]. Available: https://sid.ir/paper/399566/en

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