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Information Journal Paper

Title

Effect of High and Moderate Aerobic Exercise on Serum Fibroplast-21 Growth Factor and Paraoxonase-1 Enzyme Activity in rat with Non-Alcohol-Fatty Liver

Pages

  817-824

Abstract

 Introduction: Non-alcoholic fatty liver is a fatty liver accumulation that increases the risk of cardiovascular disease, liver carcinoma and diabetes, and physical exercises can possibly reduce liver fat. The purpose of this study was to investigate the effect of eight weeks of aerobic training on high and moderate levels on serum levels of FGF-21 and PON-1 in non-alcoholic fatty liver. Materials and Methods: To five equal groups: 1 control(healthy); 2) control(Fatty Liver); 3) saline; 4) high intensity exercise; 5) moderate intensity exercises. The period of exercise trainings was performed at 8 weeks, five times a week and 45 minutes in an exercise session. Serum samples were collected 48 hours after the last exercise session and at 12-hour fasting. One-way analysis of variance and Tukey test were used at the level of P <0. 05. Results: The levels of FGF-21had a significant decrease in the high and moderate intensity exercise groups than the control(Fatty Liver) (P≤ 0. 001). Also, the levels of PON-1 had a significant increase in the high and moderate intensity exercise groups than the control(Fatty Liver) (P≤ 0. 01), but no significantly difference between the two groups was observed. Conclusion: According to the results of this study, it seems that high and moderate intensity exercise training can decrease FGF-21 and increase paraoxonase-1 serum levels which can result in reduced risk of liver diseases in rat Nonalcoholic Fatty Liver Disease.

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    APA: Copy

    masodzade, Ghasem, BARARI, ALIREZA, AbbasiDaloii, Asieh, & FARZANEGI, PARVIN. (2021). Effect of High and Moderate Aerobic Exercise on Serum Fibroplast-21 Growth Factor and Paraoxonase-1 Enzyme Activity in rat with Non-Alcohol-Fatty Liver. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 27(6 ), 817-824. SID. https://sid.ir/paper/400858/en

    Vancouver: Copy

    masodzade Ghasem, BARARI ALIREZA, AbbasiDaloii Asieh, FARZANEGI PARVIN. Effect of High and Moderate Aerobic Exercise on Serum Fibroplast-21 Growth Factor and Paraoxonase-1 Enzyme Activity in rat with Non-Alcohol-Fatty Liver. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;27(6 ):817-824. Available from: https://sid.ir/paper/400858/en

    IEEE: Copy

    Ghasem masodzade, ALIREZA BARARI, Asieh AbbasiDaloii, and PARVIN FARZANEGI, “Effect of High and Moderate Aerobic Exercise on Serum Fibroplast-21 Growth Factor and Paraoxonase-1 Enzyme Activity in rat with Non-Alcohol-Fatty Liver,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 6 , pp. 817–824, 2021, [Online]. Available: https://sid.ir/paper/400858/en

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