SURVEY ON THE ERADICATION OF HELICOBACTER PYLORI INFECTION IN QUADRUPLE THERAPY:AMOXICILLIN, BISMUTH, OMEPRAZOLE AND CLARITHROMYCIN

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SHAFAGHI A.; NAGHIPOUR M.R.; HAGHANI SH.; AMIR MAAFI A.; ROUHI RAD M.

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Journal: JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES Year:2014 | Volume:23 | Issue:91 Page(s): 61-67

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Title

SURVEY ON THE ERADICATION OF HELICOBACTER PYLORI INFECTION IN QUADRUPLE THERAPY:AMOXICILLIN, BISMUTH, OMEPRAZOLE AND CLARITHROMYCIN

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Keywords

AMOXICILLINQ2

BISMUTHQ3

CLARITHROMYCINQ2

DRUG THERAPYQ2

COMBINATIONQ2

HELICOBACTER PYLORIQ3

OMEPRAZOLQ3

Abstract

Introduction: HELICOBACTER PYLORI infection is one of the most common infectious diseases. It can result in chronic gastritis, peptic and duodenal ulcers, MALT lymphoma and gastric cancer. The H-pylori infection can lead to a wide range of diseases and the cost spent on the eradication is much less than the cost spent on the treatment of complications of the infectionObjective: Study the efficacy of quadruple therapy (AMOXICILLIN, BISMUTH, OMEPRAZOLe and CLARITHROMYCIN) on the eradication of HELICOBACTER PYLORI infection.Materials and Methods: Between March 2011 and December 2011, we conducted a Quazi- experimental study on HELICOBACTER PYLORI infectious patients in Anzali. They were included after doing an endoscopy. Eight weeks after taking four-drugs regimen, Urea Breath Test was done to check the rate of eradication.Result: The majority of the patients were females (58.7 %). The most common symptoms before the treatment were flatulence (76 %) and epigastric pain (74.9 %). The eradication rate was 89.9 %. There were significant differences in all of the symptoms while the difference between gender and eradication rate was non-significant.Conclusion: Regardless of few side effects, all symptoms of the patients were treated significantly. As the eradication rate was 89.9 %, this quadruple drug regimen was effective on the eradication of the H-pylori.

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APA: Copy

SHAFAGHI, A., NAGHIPOUR, M.R., HAGHANI, SH., AMIR MAAFI, A., & ROUHI RAD, M.. (2014). SURVEY ON THE ERADICATION OF HELICOBACTER PYLORI INFECTION IN QUADRUPLE THERAPY:AMOXICILLIN, BISMUTH, OMEPRAZOLE AND CLARITHROMYCIN. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 23(91), 61-67. SID. https://sid.ir/paper/40093/en

Vancouver: Copy

SHAFAGHI A., NAGHIPOUR M.R., HAGHANI SH., AMIR MAAFI A., ROUHI RAD M.. SURVEY ON THE ERADICATION OF HELICOBACTER PYLORI INFECTION IN QUADRUPLE THERAPY:AMOXICILLIN, BISMUTH, OMEPRAZOLE AND CLARITHROMYCIN. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;23(91):61-67. Available from: https://sid.ir/paper/40093/en

IEEE: Copy

A. SHAFAGHI, M.R. NAGHIPOUR, SH. HAGHANI, A. AMIR MAAFI, and M. ROUHI RAD, “SURVEY ON THE ERADICATION OF HELICOBACTER PYLORI INFECTION IN QUADRUPLE THERAPY:AMOXICILLIN, BISMUTH, OMEPRAZOLE AND CLARITHROMYCIN,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 23, no. 91, pp. 61–67, 2014, [Online]. Available: https://sid.ir/paper/40093/en

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