ROLE OF TUMOR MARKERS IN BREAST CANCER RECURRENCE

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HASHEMI E.; MONTAZERI A.; AKBARI M.E.; NAJAFI M.; HAGHIGHAT SH.; KAVIANI A.

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Journal: Journal of Guilan University of Medical Sciences Year:2006 | Volume:15 | Issue:57 Page(s): 28-32

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Title

ROLE OF TUMOR MARKERS IN BREAST CANCER RECURRENCE

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Keywords

BREAST CANCERQ2

RECURRENCEQ3

TUMOR MARKERSQ3

BIOLOGICALQ3

Abstract

Introduction: The value of clinical use of TUMOR MARKERS for prediction of BREAST CANCER RECURRENCE in follow-up or level of response to treatment is still controversialObjective: In this study, the role of TUMOR MARKERS in BREAST CANCER RECURRENCE was evaluatedMaterials and Methods: One hundred and forty-one BREAST CANCER patients were entered into the study and followed up for 132 months (mean=34.0, SD=28.0). The mean age of the patients at time of diagnosis was 47.1 (SD=12.3) ranging from 23 to 81 years. Most patients (51%) were presented with stage II BREAST CANCER. 81% of the patients underwent modified radical mastectomy and the remaining 19% had breast preservation surgery. The association between clinical RECURRENCE with age, tumor size, nodal involvement, stage, type of surgery and pathology, CA15.3, CEA, P53, ER, PR, and HRE-2 status were examined by using the forward conditional logistic regression analysisResults: RECURRENCE occurred in 22% of patients during the follow up time. The results indicated that RECURRENCE was significantly predicted by the status of CA15.3 (odds ratio= 6.1, 95% CI= 1.62-23.1, P= 0.007). Conclusion: The findings showed that independent of age and other known prognostic factors; CA 15.3 is an individual factor for prediction of RECURRENCE in BREAST CANCER patients.

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APA: Copy

HASHEMI, E., MONTAZERI, A., AKBARI, M.E., NAJAFI, M., HAGHIGHAT, SH., & KAVIANI, A.. (2006). ROLE OF TUMOR MARKERS IN BREAST CANCER RECURRENCE. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 15(57), 28-32. SID. https://sid.ir/paper/40330/en

Vancouver: Copy

HASHEMI E., MONTAZERI A., AKBARI M.E., NAJAFI M., HAGHIGHAT SH., KAVIANI A.. ROLE OF TUMOR MARKERS IN BREAST CANCER RECURRENCE. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;15(57):28-32. Available from: https://sid.ir/paper/40330/en

IEEE: Copy

E. HASHEMI, A. MONTAZERI, M.E. AKBARI, M. NAJAFI, SH. HAGHIGHAT, and A. KAVIANI, “ROLE OF TUMOR MARKERS IN BREAST CANCER RECURRENCE,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 57, pp. 28–32, 2006, [Online]. Available: https://sid.ir/paper/40330/en

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