RESULTS OF RENAL TRANSPLANTATION IN PATIENTS WITH PAST HISTORY OF HEPATITIS C IN GUILAN PROVINCE

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KHOSRAVI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Guilan University of Medical Sciences Year:2005 | Volume:13 | Issue:52 Page(s): 65-70

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Title

RESULTS OF RENAL TRANSPLANTATION IN PATIENTS WITH PAST HISTORY OF HEPATITIS C IN GUILAN PROVINCE

Author(s)

KHOSRAVI M. | Issue Writer Certificate

Keywords

HEPATITIS CQ3

IMMUNOSUPPRESSIVE AGENTSQ4

KIDNEY TRANSPLANTATIONQ3

Abstract

Introduction: Patients with HEPATITIS C infection who are candidates for renal transplantation, can undergo renal transplantation if HEPATITIS C is inactive and without any liver cirrhosis. After renal transplantation due to induced immunosupression, HEPATITIS C virus can be reactivated and cause progression of liver disease as well as kidney transplant involvement (glomerulonephritis, rejection).Objective: The purpose of this study was to evaluate the results of renal transplantations in patients with a past history of HEPATITIS C involvement.Materials and Methods: This research is a cross-sectional study on 14 patients with a past history of HEPATITIS C from a total of 60 patients who had passed one year after KIDNEY TRANSPLANTATION, and between 1998- 2001, of 14 patients, 10 people had liver biopsy before transplantation. HCV-RNA was negative in the patients at the time of transplantation and after that, immunosuppressive drugs used were prednisolone, ciclospori, azathioprine, and mycophenolatemophetile. Then, data were analyzed by SPSS.10 Results: One year after transplantation, no detrimental effects were seen in those patients with a past history of HEPATITIS C on liver and transplanted kidney, life time of patient and graft survival. HCV-RNA was negative. Rejection cases were seen.in 4 casesout of 14 patients with HEPATITIS C, that was not due to HEPATITIS C. No glomerulonephritis cases were seen posttransplantation. The mean plasma creatinine was 1.18 mg/dl. No side effects of immunosupressive drugs were seen on liver of these 14 patients. Only two persons among 14 patients died because of cardiovascular problems and cytomegalovirus infection.Conclusion: This study showed that short- term consequences in our patients with a past history of HEPATITIS C infection in comparison with those who were not infected with HEPATITIS C one year post-transplantation were generally good.

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APA: Copy

KHOSRAVI, M.. (2005). RESULTS OF RENAL TRANSPLANTATION IN PATIENTS WITH PAST HISTORY OF HEPATITIS C IN GUILAN PROVINCE . JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 13(52), 65-70. SID. https://sid.ir/paper/40344/en

Vancouver: Copy

KHOSRAVI M.. RESULTS OF RENAL TRANSPLANTATION IN PATIENTS WITH PAST HISTORY OF HEPATITIS C IN GUILAN PROVINCE . JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;13(52):65-70. Available from: https://sid.ir/paper/40344/en

IEEE: Copy

M. KHOSRAVI, “RESULTS OF RENAL TRANSPLANTATION IN PATIENTS WITH PAST HISTORY OF HEPATITIS C IN GUILAN PROVINCE ,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 52, pp. 65–70, 2005, [Online]. Available: https://sid.ir/paper/40344/en

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