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Information Journal Paper

Title

CLINICAL EFFECTS OF STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION

Pages

  6-10

Abstract

 Background: With respect to the efficacy of thrombolytic agents in the treatment of acute MYOCARDIAL INFARCTION, the present study was conducted on CCU patients in Shaheed Beheshti Hospital in Kashan in 1999-2000. We have determined the efficacy of STREPTOKINASE (sk) based on antiSTREPTOKINASE before and after the treatment.Materials and methods: For this clinical trial 45 patients with acute MYOCARDIAL INFARCTION were selected. Their diagnosis was made according to their clinical manifestations as well as EKG and paraclinical studies. AntiSTREPTOKINASE was measured by ELISA method. The efficacy of STREPTOKINASE was determined by Q wave in EKG.Results: Of 45 patients, 35 had low and] 0 had high level of anti STREPTOKINASE. In 35 patients (28 with low and 10 with high antiSTREPTOKINASE) the Q wave remained unchanged following the drug administration. Drug side effects were hypotension (15.5%), bleeding (9%), and allergic reactions (4.5%). No mortality was reported.Conclusion: With respect to the high prevalence of streptococcal infections in our society, determining the antiSTREPTOKINASE level prior to the therapy is recommended. In case of low titer, we suggest STREPTOKINASE otherwise other thrombolytic agents should be administered.

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    APA: Copy

    SAFARI, MEHRI, SAMEI, A., ABDOLI, H., & ABDAR ESFAHANI, M.. (2003). CLINICAL EFFECTS OF STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION. FEYZ, 6(24), 6-10. SID. https://sid.ir/paper/40388/en

    Vancouver: Copy

    SAFARI MEHRI, SAMEI A., ABDOLI H., ABDAR ESFAHANI M.. CLINICAL EFFECTS OF STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION. FEYZ[Internet]. 2003;6(24):6-10. Available from: https://sid.ir/paper/40388/en

    IEEE: Copy

    MEHRI SAFARI, A. SAMEI, H. ABDOLI, and M. ABDAR ESFAHANI, “CLINICAL EFFECTS OF STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION,” FEYZ, vol. 6, no. 24, pp. 6–10, 2003, [Online]. Available: https://sid.ir/paper/40388/en

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