HYPOXEMIC AND HYPERCAPRIC CHANGES DURING DAY AND NIGHT IN PATIENTS WITH CHRONIC OBSTRUCTIVE
PULMONARY DISEASE

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RAZI E.; MOUSAVI SEYED GHOLAM ABAS; SHARIFI HOSSEIN

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Journal: Feyz Medical Sciences Journal Year:2001 | Volume:4 | Issue:16 Page(s): 59-67

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Information Journal Paper

Title

HYPOXEMIC AND HYPERCAPRIC CHANGES DURING DAY AND NIGHT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Author(s)

RAZI E. | MOUSAVI SEYED GHOLAM ABAS | SHARIFI HOSSEIN | Issue Writer Certificate

Keywords

HYPERCAPNIAQ3

NOCTURNAL HYPOXEMIAQ2

ARTERIAL BLOOD GASQ4

CHRONIS OBSTRUCTIVE PULMONMY DIEASEQ4

Abstract

History and Objectives: NOCTURNAL HYPOXEMIA in patients with chronic obstructive pulmonary disease (COPD) is a frequent side effect. Because there is frequent occurrence of pulmonery hypertension and cardiac al7hythmia in these patients, it is important to diagnose and treat NOCTURNAL HYPOXEMIA. In this research we investigated the changes of hypertension and hypoxemia during day and night in patients with COPD who were referred to the internal medicine ward of Shahid Beheshti Hospital in 1999. Materials and Methods: A descriptive study was conducted on 68 patients with COPD. ARTERIAL BLOOD GAS measurement was performed from radial artery in sapine position in duplicates in the day and at night. Mean PaO2 and PaCO2 during day and night and changes of mean PaO2 in different levels of HYPERCAPNIA were determined. Results: Night time decrease in PaO2 and SaO2 and increase in PaC O2 was significant compare to the day time values (day: PaO2 = 62.2±13.9 mmHg, night: 57.6±12.2.p<0.00l, day: SaO2 =88±7.5%, night: Sa O2 = 66±9%, p<0.001, day: PaCO2 = 46±7.5 mmHg, night: PaCO2 = 47.6±8 mmHg, p <0.001). The decrease in PaO2 during night in patients with PaO2<60 mmHg wasmore than inpatients with PaO2>60 mmHg (7.4±12. 7mmHg, 1.4±7.6mmHg, respectively, p=0.019). In patients with PaCO2 <45mmHg and PaCO2>45 mmHg, Pa O2 in the day and night were 66.8±12.7 mmHg, 62.1±10.4 mmHg, 57.7±13.8 mmHg, 53.1±12.4 mmHg respectively. The amount of changes in both groups was 6.97% and 7.85% respectively. Conclusions: Hypoxemia and HYPERCAPNIA are increased during night in patients with COPD. The amount decrease in NOCTURNAL HYPOXEMIA depends on its amount in the day. The amount of decrease in hypoxemia depends on the degree of HYPERCAPNIA. In patients with COPD, who has HYPERCAPNIA and hypoxemia, O2 delivery in the night and the improvement of hypoxemia is very important

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APA: Copy

RAZI, E., MOUSAVI, SEYED GHOLAM ABAS, & SHARIFI, HOSSEIN. (2001). HYPOXEMIC AND HYPERCAPRIC CHANGES DURING DAY AND NIGHT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. FEYZ, 4(16), 59-67. SID. https://sid.ir/paper/40442/en

Vancouver: Copy

RAZI E., MOUSAVI SEYED GHOLAM ABAS, SHARIFI HOSSEIN. HYPOXEMIC AND HYPERCAPRIC CHANGES DURING DAY AND NIGHT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. FEYZ[Internet]. 2001;4(16):59-67. Available from: https://sid.ir/paper/40442/en

IEEE: Copy

E. RAZI, SEYED GHOLAM ABAS MOUSAVI, and HOSSEIN SHARIFI, “HYPOXEMIC AND HYPERCAPRIC CHANGES DURING DAY AND NIGHT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE,” FEYZ, vol. 4, no. 16, pp. 59–67, 2001, [Online]. Available: https://sid.ir/paper/40442/en

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