ROLE OF SERUM PLEURAL ALBUMIN GRADIENT TO DIFFERENTIATE EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSION

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RAZI E.; SALEHI T.; MOUSAVI SEYED GHOLAM ABAS; AFAZEL M.R.

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Journal: Feyz Medical Sciences Journal Year:2000 | Volume:4 | Issue:14 Page(s): 54-59

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Title

ROLE OF SERUM PLEURAL ALBUMIN GRADIENT TO DIFFERENTIATE EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSION

Author(s)

RAZI E. | SALEHI T. | MOUSAVI SEYED GHOLAM ABAS | AFAZEL M.R. | Issue Writer Certificate

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Abstract

History and Objectives: Light's criteria in which serum and pleural LDH activity and protein levies are the most common variables to differentiate exudative from transudative pleural effusion, for the past 3 decades. Several other biochemical parameters have been suggested, one of which is serum pleural effusion albumin gradient (> 1.2: transudate, < 1.2: exudate). The present study was performed to assess diagnostic value serum and pleural gradiant in the patient with pleural effusion. Materials and Methods: A descriptive study was carried out on 76patients. In a sitting position, pleural fluid aspiration was obtained and albumin, lactate dehydrogenase (LDH), protein levels and at the same time blood total protein, LDH and albumin was obtained, on the basis of Light's criteria, pleural fluid is categorized as exudate or transudate. 76 patients presented with pleural effusion referred to the Shahid Beheshti Hospital (Kashan) were studied according to the Light's critria and gradient method. Results: According to Light's criteria, 41 patients (54%) had transudateand 35 patients (46%). had exudate. These measures were 59% and 41% respectively in gradient method. Thus discrepancy was noted in 6 cases, labeled exudate according to Light's criteria however transudate according to gradient method. Sensitivity, specificity, positive and negative predictive value were 82.9%, 95% 93.5% and 86.6% respectively for gradient method. Conclusions: Sensitivity of Light criteria is higher than albumin gradient, but the gradient method has a higher specificity for patients who are clinically suspect of transudate but labeled exudate according to Light's criteria, albumin gradient is helpful.

Cites

CAUSES OF LOW GRADIENT ASCITES IN HOSPITALIZED PATIENTS IN RASHT, 1993 –2000

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APA: Copy

RAZI, E., SALEHI, T., MOUSAVI, SEYED GHOLAM ABAS, & AFAZEL, M.R.. (2000). ROLE OF SERUM PLEURAL ALBUMIN GRADIENT TO DIFFERENTIATE EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSION. FEYZ, 4(14), 54-59. SID. https://sid.ir/paper/40486/en

Vancouver: Copy

RAZI E., SALEHI T., MOUSAVI SEYED GHOLAM ABAS, AFAZEL M.R.. ROLE OF SERUM PLEURAL ALBUMIN GRADIENT TO DIFFERENTIATE EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSION. FEYZ[Internet]. 2000;4(14):54-59. Available from: https://sid.ir/paper/40486/en

IEEE: Copy

E. RAZI, T. SALEHI, SEYED GHOLAM ABAS MOUSAVI, and M.R. AFAZEL, “ROLE OF SERUM PLEURAL ALBUMIN GRADIENT TO DIFFERENTIATE EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSION,” FEYZ, vol. 4, no. 14, pp. 54–59, 2000, [Online]. Available: https://sid.ir/paper/40486/en

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