COVID-19 diagnosis, treatment, and management: Key features you need to know

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Sadeghinejad Mohammad; SAEIDI MOHAMMAD; Momen Shiva; Saadatirad Mohammad Taha; MOHSENI FATEMEH

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Journal: Razi Journal of Medical Sciences Year:2020 | Volume:27 | Issue:3 Page(s): 138-158

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Title

COVID-19 diagnosis, treatment, and management: Key features you need to know

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Keywords

COVID-19Q1

SARS-CoV-2Q1

CoronavirusQ3

TreatmentQ3

DiagnosisQ3

PreventionQ3

ControlQ3

Abstract

In December 2019, a new type of viral pneumonia emerged in Wuhan, Hubei Province, China. Subsequently, the World Health Organization (WHO) named this unknown virus as (2019-novel Coronavirus) on January 12, 2020, and then designated as “ SARS-CoV-2” . This novel disease has no comprehensive guidelines of Treatment, Diagnosis, Control, and Prevention. An evidence-based guideline needs to be developed forthwith for frontline physicians and other involved healthcare workers in the fight against COVID-19 pneumonia. Therefore, we prepared this guideline following WHO recommendation, clinical studies, and clinical data of different studies. At present, the RT-PCR technique is approved as a determined diagnostic method for COVID-19. In addition, CT scans and Chest-X-Rays play a prominent role in follow up Treatment and recovery statues of disease, and applicable for early detection of COVID-19. Regarding the Treatment, drugs such as Chloroquine, an anti-malarial drug, and Lopinavir/Ritonavir, an anti-HIV drug, have shown significant antiviral activity against COVID-19. Other candidate drugs such as approved nucleoside analogues (favipiravir and ribavirin) and experimental nucleoside analogues (Remdesivir and Galidesivir) may have potential antiviral activity against COVID-19. Further, Pegylated Interferon Alfa-2a/b, an approved drug for the Treatment of HBV and HCV, can also be exerted to stimulate the intrinsic antiviral response in patients with COVID-19. Eventually, we further discussed other potential therapeutic agents and diagnostic strategies for the Treatment, detection, and evaluation of COVID-19 pneumonia to assist the healthcare workers in clinical sections.

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APA: Copy

Sadeghinejad, Mohammad, SAEIDI, MOHAMMAD, Momen, Shiva, Saadatirad, Mohammad Taha, & MOHSENI, FATEMEH. (2020). COVID-19 diagnosis, treatment, and management: Key features you need to know. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 27(3 ), 138-158. SID. https://sid.ir/paper/406748/en

Vancouver: Copy

Sadeghinejad Mohammad, SAEIDI MOHAMMAD, Momen Shiva, Saadatirad Mohammad Taha, MOHSENI FATEMEH. COVID-19 diagnosis, treatment, and management: Key features you need to know. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2020;27(3 ):138-158. Available from: https://sid.ir/paper/406748/en

IEEE: Copy

Mohammad Sadeghinejad, MOHAMMAD SAEIDI, Shiva Momen, Mohammad Taha Saadatirad, and FATEMEH MOHSENI, “COVID-19 diagnosis, treatment, and management: Key features you need to know,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 27, no. 3 , pp. 138–158, 2020, [Online]. Available: https://sid.ir/paper/406748/en

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