Drug-induced cholestasis: case report

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ESLAMI VAHID; Gheymati Azin

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Tehran University Medical Journal Year:2020 | Volume:78 | Issue:8 Page(s): 547-552

Download Full-Text

Persian Verion

View:

830

Download:

Cites:

Information Journal Paper

Title

Drug-induced cholestasis: case report

Author(s)

ESLAMI VAHID | Gheymati Azin | Issue Writer Certificate

Keywords

clopidogrelQ2

bilirubinQ2

hepatocellular injuryQ1

Abstract

Background: clopidogrel is an effective anti-platelet drug that is commonly prescribed for patients with atherosclerotic coronary and peripheral vascular diseases, especially after angioplasty and coronary artery bypass graft surgery. Even though this drug seems safe, there are case reports of important side effects with its use. Case Presentation: The patient was 67 years old male admitted with a diagnosis of inferior myocardial infarction who underwent angioplasty on RCA with a drug-eluting stent and was discharged with an uneventful course from hospital with medical treatment, including clopidogrel. The patient came back to the clinic 30 days later with icter, nausea and loss of appetite. The lab data showed: bilirubin (total= 5, direct=4), ALT=220, AST=100, Gama GT=830, Alk. phop=445. Virologic and imaging studies were normal. With a possible diagnosis of drug-induced hepatic injury all possible Prescribed drugs were held stepwise but bilirubin and the patient’ s symptoms did not relieve until clopidogrel has been changed. After 10 days bilirubin and his symptom relieved. Conclusion: clopidogrel is a common and partially safe drug, but it may cause hepatic injury. Considering clopidogrel side effects and its interactions seem necessary for patient management.

Cites

No record.

References

Cite

APA: Copy

ESLAMI, VAHID, & Gheymati, Azin. (2020). Drug-induced cholestasis: case report. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 78(8 ), 547-552. SID. https://sid.ir/paper/407986/en

Vancouver: Copy

ESLAMI VAHID, Gheymati Azin. Drug-induced cholestasis: case report. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2020;78(8 ):547-552. Available from: https://sid.ir/paper/407986/en

IEEE: Copy

VAHID ESLAMI, and Azin Gheymati, “Drug-induced cholestasis: case report,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 78, no. 8 , pp. 547–552, 2020, [Online]. Available: https://sid.ir/paper/407986/en

Related Journal Papers