The study of the effect of 8 weeks of interval activity on angiogenesis indexes and cardiovascular risk factor in high-fat diet mice

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AZIZI S.; FATHI M.; Valipour v.; AHMADABADI S.

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Journal: Feyz Medical Sciences Journal Year:2020 | Volume:24 | Issue:5 Page(s): 491-498

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Title

The study of the effect of 8 weeks of interval activity on angiogenesis indexes and cardiovascular risk factor in high-fat diet mice

Author(s)

AZIZI S. | FATHI M. | Valipour v. | AHMADABADI S. | Issue Writer Certificate

Keywords

Interval trainingQ1

Cardiovascular risk factorsQ1

AngiogenesisQ2

High-fat dietQ1

Abstract

Background: Physical activity has a positive effect on Angiogenesis and inflammat ion indexes, but its effect on people who intake a High-fat diet is not clear. Therefore, this study aimed to determine the effect of 8 weeks of interval activity on serum levels of angiogenes is factors and inflammatory index predicting cardiovascular disease on High-fat diet rats. Materials and Methods: In this experimental study, 30 male Wistar rats (6 weeks old) were randomly assigned in 3 groups; normal diet (n=10), High-fat diet (n=10), and High-fat dietInterval training. For the first and second groups, the training program was performed 5 days a week for 8 weeks. Before the first session and 48 hours after the last session of physical activity, blood samples were taken using the ELISA method to examine NO, VEGF, and CRP. the MANOVA test was used to analyze data Results: The results of this study showed that 8 weeks of Interval training increased significantly (p<0. 0001) NO and VEGF (P=0. 0001) levels in the High-fat diet-Interval training group compared to the control group and High-fat diet group. However, the CRP level of the High-fat diet-Interval training group decreased significantly (P=0. 0001) than the control group. Conclusion: according to the findings of this study, 8 weeks of Interval training increase some Angiogenesis factors such as NO and VEGF, which results in the probable reduction of CRP as a risk factor of cardiovascular disease.

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APA: Copy

AZIZI, S., FATHI, M., Valipour, v., & AHMADABADI, S.. (2020). The study of the effect of 8 weeks of interval activity on angiogenesis indexes and cardiovascular risk factor in high-fat diet mice. FEYZ, 24(5 ), 491-498. SID. https://sid.ir/paper/408576/en

Vancouver: Copy

AZIZI S., FATHI M., Valipour v., AHMADABADI S.. The study of the effect of 8 weeks of interval activity on angiogenesis indexes and cardiovascular risk factor in high-fat diet mice. FEYZ[Internet]. 2020;24(5 ):491-498. Available from: https://sid.ir/paper/408576/en

IEEE: Copy

S. AZIZI, M. FATHI, v. Valipour, and S. AHMADABADI, “The study of the effect of 8 weeks of interval activity on angiogenesis indexes and cardiovascular risk factor in high-fat diet mice,” FEYZ, vol. 24, no. 5 , pp. 491–498, 2020, [Online]. Available: https://sid.ir/paper/408576/en

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