PITUITARY-THYROID HORMONES AMONG HOMOZYGOUS THALASSEMIC PATIENTS REFERRED TO THE ALI-ASGHAR HOSPITAL(1995)

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SAMADI A.; TALEBI MARANDI S.

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Journal: Feyz Medical Sciences Journal Year:2000 | Volume:4 | Issue:15 Page(s): 101-106

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Title

PITUITARY-THYROID HORMONES AMONG HOMOZYGOUS THALASSEMIC PATIENTS REFERRED TO THE ALI-ASGHAR HOSPITAL(1995)

Author(s)

SAMADI A. | TALEBI MARANDI S. | Issue Writer Certificate

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Abstract

History and Objectives: Thalassemia carriership is fairly high in Iran and there is an increasing incidence of thalassemia major because of high rate marriage among thalassemic carriers. Due to complications associated with high concentration of Iron on the endocrine system, the present study was carried to investigate the pituitary-thyroid axis hormones among patients suffering from thalassemia major being treated at the Ali-Asghar Hospital of Tehran in 1995.Materials and Methods: The descriptive study was carried out on 47 patients suffering from thelassemia major (21 female and 26 male; age interval 6-21 years). Hematological tests as well as HbA2 chromatographic data was used to confirm the thalassemia major. Blood samples were taken to determine T3, T4, T3uptake, TSH and Ferritin. Distribution of hormonal changes were reported.Results: Mean value of pituitary - thyroid hormones (T3, TLf, T3uptake, TSH) among thalassemic patients was similar to normal value. However value of T3 among male patients (133ug/dL) was lower than female patients (142ug/dL). T4 level was also lower among male patients (8.9ug/dL) compared to female patients (10.1ug/dL).Ferretin levels were high among all patiets.Conclusions: In light of lower growth rate among children and adolescents suffering from thelassemia major, normal function of thyroid hormones were observed. Further research on other factors, such as growth hormone, growth hormone reserves and insulin like growth hormone-1 are recomdended.

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بررسی عملکرد تیرویید و پاراتیرویید در بیماران مبتلا به تالاسمی ماژور

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APA: Copy

SAMADI, A., & TALEBI MARANDI, S.. (2000). PITUITARY-THYROID HORMONES AMONG HOMOZYGOUS THALASSEMIC PATIENTS REFERRED TO THE ALI-ASGHAR HOSPITAL(1995). FEYZ, 4(15), 101-106. SID. https://sid.ir/paper/40895/en

Vancouver: Copy

SAMADI A., TALEBI MARANDI S.. PITUITARY-THYROID HORMONES AMONG HOMOZYGOUS THALASSEMIC PATIENTS REFERRED TO THE ALI-ASGHAR HOSPITAL(1995). FEYZ[Internet]. 2000;4(15):101-106. Available from: https://sid.ir/paper/40895/en

IEEE: Copy

A. SAMADI, and S. TALEBI MARANDI, “PITUITARY-THYROID HORMONES AMONG HOMOZYGOUS THALASSEMIC PATIENTS REFERRED TO THE ALI-ASGHAR HOSPITAL(1995),” FEYZ, vol. 4, no. 15, pp. 101–106, 2000, [Online]. Available: https://sid.ir/paper/40895/en

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