A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour

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GHARIB MASOUMEH; HOMAEI SHANDIZ FATEMEH; MADDAH GHODRATOLLAH; Mehdizadeh Behnoush

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2021 | Volume:24 | Issue:3 Page(s): 95-100

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Title

A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour

Author(s)

GHARIB MASOUMEH | HOMAEI SHANDIZ FATEMEH | MADDAH GHODRATOLLAH | Mehdizadeh Behnoush | Issue Writer Certificate

Keywords

AnaplasiaQ1

case reportQ1

Juvenile granulosa cell tumorQ1

Ovarian malignancyQ1

Abstract

Introduction: Anaplastic variant of Juvenile granulosa cell tumor is one of the rarest ovarian malignancies. The aim of this study is to describe a case of anaplastic variant ovarian granulosa cell tumor in a 14-year-old girl with presentation of abnormal uterine bleeding and gradual abdominal enlargement. Case presentation: The patient at the time of diagnosis with an inhibin A and B more than 500 Pg/ml and ovarian mass of about 30×20×15 cm underwent unilateral salpingo-oophorectomy and Juvenile granulosa cell tumor was diagnosed with no follow-up. She has referred with ascites, recurrent mass and distance metastasis of liver after 10 months. The patient underwent four courses of BEP (Bleomycin, Etoposide, Cisplatin)and five courses of paclitaxel and carboplatin. Then, she underwent laparotomy for metastasectomy, which was not successful due to the extent of involvement. Eventually, she died six months after the second surgery. Conclusion: This case report confirms the need for accurate follow-up of patients with Juvenile granulosa cell tumor and appropriate justification for the patient and their caregiver to prescribe needed adjuvant therapies to prevent recurrence.

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APA: Copy

GHARIB, MASOUMEH, HOMAEI SHANDIZ, FATEMEH, MADDAH, GHODRATOLLAH, & Mehdizadeh, Behnoush. (2021). A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 24(3 ), 95-100. SID. https://sid.ir/paper/409784/en

Vancouver: Copy

GHARIB MASOUMEH, HOMAEI SHANDIZ FATEMEH, MADDAH GHODRATOLLAH, Mehdizadeh Behnoush. A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2021;24(3 ):95-100. Available from: https://sid.ir/paper/409784/en

IEEE: Copy

MASOUMEH GHARIB, FATEMEH HOMAEI SHANDIZ, GHODRATOLLAH MADDAH, and Behnoush Mehdizadeh, “A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 24, no. 3 , pp. 95–100, 2021, [Online]. Available: https://sid.ir/paper/409784/en

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