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Information Journal Paper

Title

A RETROSPECTIVE STUDY OF CLINICAL AND PARACLINICAL CHARACTERISTICS OF INSULINOMA DURING THE LAST TWO DECADES

Author(s)

 ARDESHIR LARIJANI MOHAMMAD BAGHER | ZAHEDI F. | MOOSAVI LAR SH.S. | Issue Writer Certificate 

Pages

  97-103

Abstract

 lnsulinomas are rare diseases but remain the most common causes of HYPOGLYCEMIA secondary to endogenous hyperinsulinism, and should be considered in patients with HYPOGLYCEMIA. This study was designed to determine the clinical and paraclinical characteristics of INSULINOMA. We retrospectively reviewed medical records of patients with biochemical or histologically confirmed INSULINOMAs in hospitals of Tehran university of medical sciences. The data was analyzed by statistical software of SPSS.Mean age at diagnosis was 39 years and 47% of patients were females and 53% males. No difference was noted between males and females with respect to age of diagnosis. The mean duration of symptoms before diagnosis was 39.9 months. As many as 84% of patients were mistakenly admited by other diagnoses such neurologic (CVA, epilepsy) and psychiatric disorders. Noradrenergic and neuroglycopenic symptoms were recorded in 89.6 and 97 percent of patients, respectively. For tumor localization, transabdominal ultrasonography, pancreatic CT Scan and celiac angiography had been done. Surgical treatment had been done for 55 patients. The mean diameter of tumor was 2.9 cm and 87.8% of tumors were single and 94.2% of them were benign. Outcome of surgery was good in 70% of patients.This review showed that misdiagnosis of INSULINOMA is a common problem that may lead to serious complications and even death. The comparison of characteristics of INSULINOMA in our patients compared with other countries showed a lower age of occurrence, clinical presentation accompanied by convulsion, stupor and dementia, and a bigger size of the tumor. It is recommended that new technologies and skilled persons be used for tumor localization.

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    APA: Copy

    ARDESHIR LARIJANI, MOHAMMAD BAGHER, ZAHEDI, F., & MOOSAVI LAR, SH.S.. (2004). A RETROSPECTIVE STUDY OF CLINICAL AND PARACLINICAL CHARACTERISTICS OF INSULINOMA DURING THE LAST TWO DECADES. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 22(2), 97-103. SID. https://sid.ir/paper/41158/en

    Vancouver: Copy

    ARDESHIR LARIJANI MOHAMMAD BAGHER, ZAHEDI F., MOOSAVI LAR SH.S.. A RETROSPECTIVE STUDY OF CLINICAL AND PARACLINICAL CHARACTERISTICS OF INSULINOMA DURING THE LAST TWO DECADES. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2004;22(2):97-103. Available from: https://sid.ir/paper/41158/en

    IEEE: Copy

    MOHAMMAD BAGHER ARDESHIR LARIJANI, F. ZAHEDI, and SH.S. MOOSAVI LAR, “A RETROSPECTIVE STUDY OF CLINICAL AND PARACLINICAL CHARACTERISTICS OF INSULINOMA DURING THE LAST TWO DECADES,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 22, no. 2, pp. 97–103, 2004, [Online]. Available: https://sid.ir/paper/41158/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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