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Information Journal Paper

Title

Antibiotic Susceptibility Profile of Clostridium Difficile Bacteria Isolated from Older Residents of a Nursing Home in Iran

Pages

  496-505

Abstract

 Objectives Clostridium difficile (C. diff) is a gram-positive anaerobic bacterium knwon as the most common cause of nosocomial diarrhea in nursing homes. The Antibiotic susceptibility profile is the basic way for successful treatment due to antimicrobial resistance. This present study aims to assess the Antibiotic susceptibility profile of C. diff isolated from older residents of a nursing home in Tehran, Iran. Methods & Materials Forty-two isolates of C. diff were used in this study collected from 289 residents of Kahrizak Nursing Home. Antibiotic susceptibility testing was conducted by using disk-diffusion method, agar dilution method, and Epsilometer test (E-test). Results All C. diff strains were susceptible to Metronidazole, Vancomycin, Rifampicin, Linezolid and Tigecycline. By using the disk-diffusion method, the highest rate of resistance was related to Clindamycin (100%), Levofloxacin (96. 2%), Imipenem (81%), Azithromycin (61%) and Erythromycin (54. 8%). All C. diff strains were susceptible to Metronidazole under E-test. Furthermore, 100% and 59. 5% of strains were susceptible to Vancomycin and Erythromycin, respectively under agar dilution test. Conclusion C. diff strains are sensitive to Vancomycin and Metronidazole. These two antibiotics can be used to treat C. diff infections in Older adults. The disk diffusion method can be used as a screening test to determine antibiotic resistance.

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    APA: Copy

    GHASEMI, AHMAD, & MOHABATI MOBAREZ, ASHRAF. (2021). Antibiotic Susceptibility Profile of Clostridium Difficile Bacteria Isolated from Older Residents of a Nursing Home in Iran. IRANIAN JOURNAL OF AGEING, 15(4 ), 496-505. SID. https://sid.ir/paper/411702/en

    Vancouver: Copy

    GHASEMI AHMAD, MOHABATI MOBAREZ ASHRAF. Antibiotic Susceptibility Profile of Clostridium Difficile Bacteria Isolated from Older Residents of a Nursing Home in Iran. IRANIAN JOURNAL OF AGEING[Internet]. 2021;15(4 ):496-505. Available from: https://sid.ir/paper/411702/en

    IEEE: Copy

    AHMAD GHASEMI, and ASHRAF MOHABATI MOBAREZ, “Antibiotic Susceptibility Profile of Clostridium Difficile Bacteria Isolated from Older Residents of a Nursing Home in Iran,” IRANIAN JOURNAL OF AGEING, vol. 15, no. 4 , pp. 496–505, 2021, [Online]. Available: https://sid.ir/paper/411702/en

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