EVALUATION OF GHRELIN AND LEPTIN IN PATIENTS WITH THYROID MALFUNCTION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOSHTAGHI KASHANIAN GH.R.; GHOLAM HOSSEINIAN A.; SANJARI M.; KOR M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Kerman University of Medical Sciences Year:2005 | Volume:12 | Issue:4 Page(s): 219-227

Download Full-Text

Persian Verion

View:

1,745

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF GHRELIN AND LEPTIN IN PATIENTS WITH THYROID MALFUNCTION

Author(s)

MOSHTAGHI KASHANIAN GH.R. | GHOLAM HOSSEINIAN A. | SANJARI M. | KOR M. | Issue Writer Certificate

Keywords

GHRELINQ2

LEPTINQ2

HYPERTHYROIDISMQ4

HYPOTHYROIDISM AND BMIQ4

Abstract

Introduction: LEPTIN and GHRELIN are hormones that have been discovered in the last decade and were shown to be involved in appetite and metabolism regulation and body weight. Thyroid hormones are also involved in general metabolism and changes in their circulating levels bring about changes in appetite and body weight. Results of animal and human studies regarding LEPTINlevel and its relation to thyroid hormones are opposing each other, and there is no data about GHRELIN level in thyroid malfunction. To determine the relation between thyroid function and circulating levels of GHRELIN and LEPTIN, we evaluated serum concentration of these hormones in patients with untreated thyroid malfunction. Method: Thirty hyperthyroid and 30 hypothyroid females that were aged between 14-52 years and 30 healthy females with the same age range (control group) were randomly selected. From each participant 5 ml of fasting blood was collected and after processing, serum levels of T4, T3, T3-uptake, TSH, LEPTIN and GHRELIN were evaluated by radio-immunoassay or enzyme-link immunoassay methods. Results: Evaluated results showed that neither GHRELIN nor LEPTIN levels show significant change in patients with thyroid malfunction. But there was a positive significant correlation between LEPTIN level and BMI of all participants (r=0.41, P<0.01). In addition, there were negative significant correlations between GHRELIN and thyroid hormones (r=0.27, P<0.05). Conclusion: The present results show that LEPTIN variation is due to BMI. Furthermore, negative and weak correlation between thyroid hormones and GHRELIN may indicate that increase in appetite of hyperthyroid patients and its decrease in hypothyroid patients are not due to circulating level of GHRELIN.

Cites

No record.

References

No record.

Cite

APA: Copy

MOSHTAGHI KASHANIAN, GH.R., GHOLAM HOSSEINIAN, A., SANJARI, M., & KOR, M.. (2005). EVALUATION OF GHRELIN AND LEPTIN IN PATIENTS WITH THYROID MALFUNCTION. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 12(4), 219-227. SID. https://sid.ir/paper/413/en

Vancouver: Copy

MOSHTAGHI KASHANIAN GH.R., GHOLAM HOSSEINIAN A., SANJARI M., KOR M.. EVALUATION OF GHRELIN AND LEPTIN IN PATIENTS WITH THYROID MALFUNCTION. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;12(4):219-227. Available from: https://sid.ir/paper/413/en

IEEE: Copy

GH.R. MOSHTAGHI KASHANIAN, A. GHOLAM HOSSEINIAN, M. SANJARI, and M. KOR, “EVALUATION OF GHRELIN AND LEPTIN IN PATIENTS WITH THYROID MALFUNCTION,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 4, pp. 219–227, 2005, [Online]. Available: https://sid.ir/paper/413/en

Related Journal Papers