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Information Journal Paper

Title

Stereological Study of the renal structures volume in L-arginine-induced pancreatitis and therapeutically effect of pancreatin

Pages

  250-258

Abstract

 Introduction: The aim of this study was to stereological evaluate of the protective effect of pancreatin on morphological changes in Mice kidney after treatment with L-Arginine. Materials and Methods: To conduct research, 50 adult male rats weighing 30± 2 gr were divided into 5 groups (equal). In the control group, no administration was made. The Pancreatitis induction groups received 2 doses of 300 and 400 mg/100 g body weight of L-Arginine. To the induction groups with two different doses, therapeutic drug was prescribed 3. 5 pp. of lipase-pancreatin. All treatments were received for 3 consecutive days once a day from L-Arginine solution and 72 hours later, a lipase-pancreatin solution was administered to groups of Pancreatitis for 20 days. Results: The results showed that due to experimental Pancreatitis, except for medulla volume, decreasing volume of renal cortex, proximal and distal Convoluted Tubules, and glomeruli was observed in the treated groups compared to the control group. By the administration of pancreatin lipase along with L-Arginine, mean volume values of factors such as mean volume of renal cortex, proximal Convoluted Tubules and glomeruli, have gotten closed to the control group. Conclusion: According to a final review of the findings, lipase-pancreatin solution may be partially effective in mitigating the effects of Pancreatitis induced by high doses of L-Arginine.

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    Cite

    APA: Copy

    Fatahian Dehkordi, Rahmat Allah, YAZDANPANAH, MOHAMMAD JAVAD, & Khetvan, Reza. (2021). Stereological Study of the renal structures volume in L-arginine-induced pancreatitis and therapeutically effect of pancreatin. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 28(2 ), 250-258. SID. https://sid.ir/paper/413651/en

    Vancouver: Copy

    Fatahian Dehkordi Rahmat Allah, YAZDANPANAH MOHAMMAD JAVAD, Khetvan Reza. Stereological Study of the renal structures volume in L-arginine-induced pancreatitis and therapeutically effect of pancreatin. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;28(2 ):250-258. Available from: https://sid.ir/paper/413651/en

    IEEE: Copy

    Rahmat Allah Fatahian Dehkordi, MOHAMMAD JAVAD YAZDANPANAH, and Reza Khetvan, “Stereological Study of the renal structures volume in L-arginine-induced pancreatitis and therapeutically effect of pancreatin,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 2 , pp. 250–258, 2021, [Online]. Available: https://sid.ir/paper/413651/en

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