Effect of Eight-Week Aerobic Moderate-Intensity Continuous Training on Il-1β and Il-13 Levels of Soleus Muscle Tissue in Male Diabetic Rats

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Nabilpour Maghsoud; Sadeghi Abbas

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Journal Paper

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Journal: Iranian Journal of Diabetes and Metabolism Year:2021 | Volume:21 | Issue:3 Page(s): 129-138

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Information Journal Paper

Title

Effect of Eight-Week Aerobic Moderate-Intensity Continuous Training on Il-1β and Il-13 Levels of Soleus Muscle Tissue in Male Diabetic Rats

Author(s)

Nabilpour Maghsoud | Sadeghi Abbas | Issue Writer Certificate

Keywords

InflammationQ2

Aerobic exerciseQ2

DiabetesQ2

Interleukin 1-βQ1

Interleukin-13Q1

Abstract

Background: One consequence of Diabetes mellitus is increased Inflammation, which is exacerbated by training. The objective of this study was to evaluate the effect of eight weeks of aerobic moderate-intensity continuous training on Interleukin-1 beta, Interleukin-13 responses in male Wistar diabetic rats. Methods: 36 diabetic rats were randomly assigned into 3 equal groups (control (C), diabetic (D), and Diabetes + training (D + T)), and subjected to eight weeks of aerobic moderate-intensity continuous training intensity at the first: the10 min on 10m/min and at the final: 55min on 26m/min speed. Interleukin-1 and Interleukin-13 were measured in soleus muscle tissue to examine the pro-inflammatory and anti-inflammatory indicators. ANOVA and Scheffe post hoc tests were used for data analysis. Results: Induction of Diabetes caused a significant increase in IL-1β and IL-13 (P<0. 001) and continuous exercise intervention also significantly reduced IL-1β levels in diabetic rats (P = 0. 02). However, there was no significant change in IL-13 in D + T group compared to D group (P = 0. 985). Conclusion: According to the results of this study, the effect of Aerobic exercise is probably a positive effect on reducing the pro-inflammatory index of IL-1β and no effect on the anti-inflammatory index of IL-13 in diabetic rats. However, definitive confirmation of these results requires further research in this area.

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APA: Copy

Nabilpour, Maghsoud, & Sadeghi, Abbas. (2021). Effect of Eight-Week Aerobic Moderate-Intensity Continuous Training on Il-1β and Il-13 Levels of Soleus Muscle Tissue in Male Diabetic Rats. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 21(3 ), 129-138. SID. https://sid.ir/paper/413896/en

Vancouver: Copy

Nabilpour Maghsoud, Sadeghi Abbas. Effect of Eight-Week Aerobic Moderate-Intensity Continuous Training on Il-1β and Il-13 Levels of Soleus Muscle Tissue in Male Diabetic Rats. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2021;21(3 ):129-138. Available from: https://sid.ir/paper/413896/en

IEEE: Copy

Maghsoud Nabilpour, and Abbas Sadeghi, “Effect of Eight-Week Aerobic Moderate-Intensity Continuous Training on Il-1β and Il-13 Levels of Soleus Muscle Tissue in Male Diabetic Rats,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 21, no. 3 , pp. 129–138, 2021, [Online]. Available: https://sid.ir/paper/413896/en

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