FRUCTOSAMIN AND CONTROL OF DIABETES AN INTRODUCION OF A NEW MODEL

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ARDESHIR LARIJANI MOHAMMAD BAGHER; PAZHOUHI M.; HOSSEINI GOUHARI L.; JAVADI E.; SHAFAE A.; MAHMOUDI M.

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Journal: Journal of Medical Council of Iran Year:2001 | Volume:19 | Issue:1 Page(s): 21-27

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Title

FRUCTOSAMIN AND CONTROL OF DIABETES AN INTRODUCION OF A NEW MODEL

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Keywords

DIABETIC CONTROLQ4

SERUM FRUCTOSAMINEQ4

SERUM PROTEIN GLYCOSILATIONQ4

Abstract

The major aim of all therapeutic programs in diabetes mellitus is maintenance of blood glucose level in normal range. At present, in achieving this purpose, measurement of fasting blood sugar (FBS) and glycosilated hemoglobin A1 (HbA1) are commonly used as glycemic control indices. Since the above two tests cannot depict the metabolic state of the patient under all conditions, thus this study was conducted with the aim to control diabetic patients by determining serum fructosamin levels allowing a direct surveillance over the mean blood sugar levels during tine intervals when assessment of it with other indices was not feasible.Serum fructosamin was evaluated in 90 diabetic patients not adequately controlled (Type І, ІІ), for 3 times with an interval of 2 weeks and in 100 normal samples as a medium index glycemic control. The method is colorimetric on the base of nitroblue tetrazulium reduction. According to the results serum fructosamin in comparison HbA1 is a sensitive parameter to show fluctuation of blood glucose, furthermore some agents such as age, sex, chronic disease, hematolgic disease and drug consumption don’t effect the serum fructosamin level.In this study direct estimation of mean blood glucose at 1-3 past week with application of multiple regression analysis, provided a diagram allowing monitoring blood glucose on the base of fructosamin concentration. By this method, in uncontrolled diabetic patients, using the above model and assessment of serum fructosamin levels, the course of treatment and improvement secondary to blood glucose control with the initiation of treatment and changes in treatment can be easily assessed and controlled.So, for assurance to do effective treatment, fructosamin in comparison with other glycemic parameter, has peculiar importance.

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APA: Copy

ARDESHIR LARIJANI, MOHAMMAD BAGHER, PAZHOUHI, M., HOSSEINI GOUHARI, L., JAVADI, E., SHAFAE, A., & MAHMOUDI, M.. (2001). FRUCTOSAMIN AND CONTROL OF DIABETES AN INTRODUCION OF A NEW MODEL. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 19(1), 21-27. SID. https://sid.ir/paper/41461/en

Vancouver: Copy

ARDESHIR LARIJANI MOHAMMAD BAGHER, PAZHOUHI M., HOSSEINI GOUHARI L., JAVADI E., SHAFAE A., MAHMOUDI M.. FRUCTOSAMIN AND CONTROL OF DIABETES AN INTRODUCION OF A NEW MODEL. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2001;19(1):21-27. Available from: https://sid.ir/paper/41461/en

IEEE: Copy

MOHAMMAD BAGHER ARDESHIR LARIJANI, M. PAZHOUHI, L. HOSSEINI GOUHARI, E. JAVADI, A. SHAFAE, and M. MAHMOUDI, “FRUCTOSAMIN AND CONTROL OF DIABETES AN INTRODUCION OF A NEW MODEL,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 19, no. 1, pp. 21–27, 2001, [Online]. Available: https://sid.ir/paper/41461/en

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